SCHEMBL7616740

SCHEMBL7616740

OC[C@H]1OC(c2ccccc2)O[C@H]2[C@@H]1OC(O)[C@@H]2O

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 6/20 0.42
TXNRD1 Q16881 1/20 0.40
TXNRD3 Q86VQ6 1/20 0.40
TXNRD2 Q9NNW7 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.37
CYP2C19 P33261 2/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
MAPT P10636 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HK1 P19367 1/20 0.35
HK2 P52789 1/20 0.35
ALDH1A1 P00352 2/20 0.34
TSHR P16473 2/20 0.34
LMNA P02545 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7154382 0.90 SLC5A2 (0.41) SLC5A2TXNRD1TXNRD3TXNRD2CYP2C19
SCHEMBL31135220 0.90 SLC5A2 (0.41) SLC5A2TXNRD1TXNRD3TXNRD2CYP2C19
SCHEMBL7151167 0.87 SLC5A2 (0.41) SLC5A2TXNRD1TXNRD3TXNRD2L3MBTL1
SCHEMBL13053681 0.87 SLC5A2 (0.41) SLC5A2TXNRD1TXNRD3TXNRD2L3MBTL1
SCHEMBL7152367 0.87 SLC5A2 (0.41) SLC5A2TXNRD1TXNRD3TXNRD2L3MBTL1
SCHEMBL24579840 0.87 SLC5A2 (0.41) SLC5A2TXNRD1TXNRD3TXNRD2L3MBTL1
SCHEMBL7155412 0.83 SLC5A2 (0.53) SLC5A2CYP2C19CYP3A4CYP2D6MAPT
SCHEMBL4633309 0.83 SLC5A2 (0.53) SLC5A2CYP2C19CYP3A4CYP2D6MAPT
SCHEMBL7154496 0.81 MEN1 (0.52) SLC5A2L3MBTL1CYP2C19MEN1KMT2A
SCHEMBL7149673 0.81 TXNRD1 (0.40) SLC5A2TXNRD1TXNRD3TXNRD2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0852243-B1 POLYETHYLENE OXIDES HAVING SACCHARIDE RESIDUE AT ONE END AND DIFFERENT FUNCTIONAL GROUP AT ANOTHER END, AND PROCESS FOR PRODUCING THE SAME KATAOKA KAZUNORI (JP) 2002-10-30 EP disclosed
US-6090317-A POLYETHYLENE OXIDE-POLYLACTONE BLOCK POLYMER WHICH HAS A SUGAR RESIDUE AT ITS TERMINAL. Kataoka, Kazunori (JP) 2000-07-18 US disclosed
US-5973069-A BIOAVAILABILITY; DRUG DELIVERY; MEDICAL DIAGNOSIS KAZUNORI KATAOKA (JP) 1999-10-26 US disclosed
EP-0852243-A1 POLYETHYLENE OXIDES HAVING SACCHARIDE RESIDUE AT ONE END AND DIFFERENT FUNCTIONAL GROUP AT ANOTHER END, AND PROCESS FOR PRODUCING THE SAME Kataoka, Kazunori (JP) 1998-07-08 EP disclosed