Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 4/20 | 0.53 |
| ▸ | HTR1B | P28222 | 2/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.50 |
| ▸ | TUBB | P07437 | 2/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.50 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.50 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.50 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.50 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.50 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29445066 | 0.98 | RHEB (0.54) | RHEBHTR1BTUBB4ATUBBTUBA3C | |
| SCHEMBL321761 | 0.98 | RHEB (0.54) | RHEBHTR1BTUBB4ATUBBTUBA3C | |
| SCHEMBL29992707 | 0.98 | RHEB (0.54) | RHEBHTR1BTUBB4ATUBBTUBA3C | |
| Ethyne SCHEMBL28266951 | 0.94 | RHEB (0.51) | RHEBHTR1BTUBB4ATUBBTUBA3C | |
| Acetonitrile SCHEMBL28669017 | 0.89 | RHEB (0.47) | RHEBHTR1BTUBB4ATUBBTUBA3C | |
| SCHEMBL4206976 | 0.89 | RHEB (0.48) | RHEBHTR1BTUBB4ATUBBTUBA3C | |
| SCHEMBL29992621 | 0.85 | RHEB (0.50) | RHEBHTR1BTUBB4ATUBBTUBA3C | |
| SCHEMBL26965656 | 0.82 | RHEB (0.51) | RHEBHTR1BTUBB4ATUBBTUBA3C | |
| SCHEMBL3001554 | 0.82 | TUBB4A (0.60) | RHEBTUBB4ATUBBTUBA3CTUBA1B | |
| Phenylacetylene SCHEMBL28267516 | 0.82 | RHEB (0.46) | RHEBHTR1BTUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6433001-B1 | SEPTIC SHOCK, ALLERGIC RHINITIS, RHEUMATIC ARTHRITIS, ADULT RESPIRATORY DISTRESS SYNDROME, BRONCHIAL ASTHMA, TRAUMA, AND PANCREATITIS TREATMENT | ELI LILLY AND COMPANY | 2002-08-13 | — | — | US | disclosed |