Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 16/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.44 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7645569 | 0.90 | PLA2G1B (0.55) | PLA2G1BPLA2G2A | |
| SCHEMBL7645530 | 0.89 | PLA2G1B (0.48) | PLA2G1BPLA2G2A | |
| SCHEMBL7187199 | 0.85 | PLA2G1B (0.55) | PLA2G1BPLA2G2A | |
| SCHEMBL7641251 | 0.84 | PLA2G1B (0.58) | PLA2G1BPLA2G2A | |
| SCHEMBL7643276 | 0.81 | PLA2G1B (0.43) | PLA2G1BPLA2G2A | |
| SCHEMBL7641632 | 0.79 | PLA2G1B (0.54) | PLA2G1BPLA2G2A | |
| SCHEMBL13888555 | 0.79 | PLA2G1B (0.57) | PLA2G1BPLA2G2A | |
| SCHEMBL7946058 | 0.79 | PLA2G2A (0.54) | PLA2G1BPLA2G2A | |
| SCHEMBL7643254 | 0.78 | PLA2G1B (0.52) | PLA2G1BPLA2G2A | |
| SCHEMBL7643172 | 0.77 | PLA2G2A (0.51) | PLA2G1BPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265607-A2 | METHOD FOR THE TREATMENT OF RENAL DYSFUNCTION WITH sPLA 2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001066111-A1 | COMPOSITIONS CONTAINING POTENTIAL SPLA2 INHIBITORS FOR THE TREATMENT OF PAIN | ELI LILLY AND COMPANY (US) | 2001-09-13 | — | — | WO | disclosed |
| WO-2001066110-A2 | METHOD FOR THE TREATMENT OF RENAL DYSFUNCTION WITH sPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-09-13 | — | — | WO | disclosed |