Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159676 | 0.81 | CYP3A4 (0.37) | GABRA1GABRB2TDP1 | |
| SCHEMBL20609875 | 0.79 | GABRA1 (0.34) | GABRA1GABRB2 | |
| SCHEMBL21810673 | 0.79 | GABRA1 (0.34) | GABRA1GABRB2 | |
| SCHEMBL752311 | 0.78 | GABRA1 (0.41) | GABRA1GABRB2 | |
| SCHEMBL9623520 | 0.77 | GABRA1 (0.47) | GABRA1GABRB2MAPK1TDP1 | |
| SCHEMBL194319 | 0.76 | GABRA1 (0.35) | GABRA1GABRB2 | |
| SCHEMBL20625199 | 0.76 | GABRA1 (0.32) | GABRA1GABRB2MAPK1TDP1 | |
| SCHEMBL112208 | 0.75 | CYP3A4 (0.38) | GABRA1GABRB2TDP1 | |
| SCHEMBL10585418 | 0.74 | CYP3A4 (0.50) | GABRA1GABRB2TDP1 | |
| SCHEMBL191769 | 0.74 | GABRA1 (0.50) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214087-A1 | COMBINATION TREATMENT WITH IL-1RA AND COMPOUNDS THAT INHIBIT IL-1 PROCESSING AND RELEASE | Pfizer Products Inc. (US) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001019390-A1 | COMBINATION TREATMENT WITH IL-1RA AND DIARYL SULPHONYL UREA COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2001-03-22 | — | — | WO | disclosed |