Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.70 |
| ▸ | ESR1 | P03372 | 9/20 | 0.69 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.69 |
| ▸ | LTA4H | P09960 | 1/20 | 0.60 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.58 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7670336 | 0.99 | F2 (0.69) | F2ESR1ESR2LTA4HENPP3 | |
| SCHEMBL6595906 | 0.94 | F2 (0.80) | F2ESR1ESR2LTA4H | |
| SCHEMBL6141705 | 0.92 | F2 (0.62) | F2ESR1ESR2LTA4H | |
| SCHEMBL7410171 | 0.90 | F2 (0.63) | F2ESR1ESR2LTA4H | |
| SCHEMBL6594039 | 0.90 | F2 (0.81) | F2ESR1ESR2ENPP3ENPP1 | |
| SCHEMBL6141711 | 0.89 | F2 (0.62) | F2ESR1ESR2 | |
| SCHEMBL6172878 | 0.89 | ESR1 (0.66) | F2ESR1ESR2LTA4H | |
| SCHEMBL6597343 | 0.89 | F2 (0.60) | F2ESR1ESR2ENPP3ENPP1 | |
| SCHEMBL6597349 | 0.89 | F2 (0.60) | F2ESR1ESR2ENPP3ENPP1 | |
| SCHEMBL6597350 | 0.89 | F2 (0.60) | F2ESR1ESR2ENPP3ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703231-B1 | 2-(4-Hydroxyphenyl)benzothiophene compounds, compositions and methods for alleviating the symptoms of post-menopause syndrome | LILLY CO ELI (US) | 2002-05-02 | — | — | EP | disclosed |
| WO-1996009041-A1 | BENZOTHIOPHENE COMPOUNDS, COMPOSITIONS, AND METHODS | ELI LILLY AND COMPANY (US) | 1996-03-28 | — | — | WO | disclosed |
| EP-0703231-A1 | 2-(4-Hydroxyphenyl)benzothiophene compounds, compositions and methods for alleviating the symptoms of post-menopause syndrome | ELI LILLY AND COMPANY (US) | 1996-03-27 | — | — | EP | disclosed |
| US-5492921-A | PREVENTING RESTENOSIS | ELI LILLY AND COMPANY (US) | 1996-02-20 | — | — | US | disclosed |
| US-5484798-A | Benzothiopene compounds, compositions, and method of inhibiting restenosis | ELI LILLY AND COMPANY (US) | 1996-01-16 | — | — | US | disclosed |