Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.52 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.52 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7058501 | 0.95 | KDM4E (0.57) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL7057179 | 0.89 | ICAM1 (0.49) | ALDH1A1KDM4EHTTMEN1KMT2A | |
| SCHEMBL4131544 | 0.80 | KDM4E (0.45) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL8933525 | 0.80 | KDM4E (0.58) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL15517761 | 0.80 | KDM4E (0.58) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL15516982 | 0.79 | KDM4E (0.57) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL7057425 | 0.76 | ICAM1 (0.48) | GAAHTTMEN1KMT2AMAPK1 | |
| SCHEMBL8242672 | 0.76 | KDM4E (0.54) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL7057872 | 0.75 | CDK8 (0.59) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL4343748 | 0.74 | ALDH1A1 (0.73) | ALDH1A1KDM4EHPGDGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181296-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000075145-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-12-14 | — | — | WO | disclosed |