Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL762745 | 0.88 | ALDH1A1 (0.35) | ALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL762746 | 0.82 | DHODH (0.38) | HTR2CDHODHTGFBR1KDM4ENPC1 | |
| SCHEMBL17465783 | 0.78 | KDM4E (0.41) | HTR2CDHODHTGFBR1KDM4ENPC1 | |
| SCHEMBL12014716 | 0.78 | ALDH1A1 (0.38) | ALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL15158406 | 0.77 | HTR2C (0.41) | HTR2CDHODHTGFBR1KDM4ENPC1 | |
| SCHEMBL15158450 | 0.77 | KDM4E (0.41) | HTR2CDHODHTGFBR1KDM4ENPC1 | |
| SCHEMBL15158508 | 0.77 | KDM4E (0.41) | HTR2CDHODHTGFBR1KDM4ENPC1 | |
| SCHEMBL15178585 | 0.77 | HTR2C (0.39) | HTR2CDHODHTGFBR1KDM4ENPC1 | |
| SCHEMBL16485340 | 0.76 | PDK2 (0.38) | HTR2CDHODHTGFBR1NPC1HPGD | |
| SCHEMBL762280 | 0.76 | PDK2 (0.35) | HTR2CDHODHTGFBR1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138668-B2 | Benzo[a]fluoranthene compound and organic light emitting device using the same | CANON KABUSHIKI KAISHA (JP) | 2012-03-20 | — | — | US | disclosed |
| US-8138668-B2 | Benzo[a]fluoranthene compound and organic light emitting device using the same | CANON KABUSHIKI KAISHA (JP) | 2012-03-20 | — | — | US | disclosed |
| US-20100019661-A1 | BENZO[a]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2010-01-28 | — | — | US | disclosed |
| US-20100019661-A1 | BENZO[a]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2010-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100019661-A1 | BENZO[a]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | AFF1, AFF2, CYP1A1 | HTR2C 2444/4885DHODH 1822/4885TGFBR1 1071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.