Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 3/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7618250 | 0.96 | FAAH (0.47) | TP53TSHRPLA2G4BNR1H4LTA4H | |
| SCHEMBL7624611 | 0.88 | ITGB1 (0.55) | TP53TSHRPLA2G4BNR5A1NPC1 | |
| SCHEMBL7622700 | 0.87 | ITGB1 (0.53) | TP53TSHRPLA2G4BNR1H4LTA4H | |
| SCHEMBL7625207 | 0.86 | TP53 (0.46) | TP53TSHRPLA2G4BNR1H4NR5A1 | |
| SCHEMBL7617564 | 0.85 | PPARA (0.48) | TP53TSHRPLA2G4BNR1H4 | |
| SCHEMBL7618443 | 0.83 | FAAH (0.46) | TP53TSHRPLA2G4BNR1H4RARB | |
| SCHEMBL7621064 | 0.82 | PPARA (0.48) | TP53TSHRPLA2G4BLMNALTA4H | |
| SCHEMBL7623578 | 0.79 | NPC1 (0.44) | TP53TSHRNPC1LMNA | |
| SCHEMBL15760403 | 0.78 | TP53 (0.63) | TP53TSHRPLA2G4BNR5A1RARB | |
| SCHEMBL29715644 | 0.78 | GGPS1 (0.46) | PLA2G4BNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6486228-B2 | BIS-ACYLPHOSPHINE OXIDES AND ACYLPHOSPHINE OXIDES FOR CURING PHOTOPOLYMERIZABLE COMPOSITIONS WITHOUT YELLOWING; USE IN WHITE SURFACE COATINGS, AS NEGATIVE PHOTORESISTS, IN PRINTING PLATES | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-11-26 | — | — | US | disclosed |
| US-20010036978-A1 | Photoinitiator combinations | IGM GROUP B.V. (NL) | 2001-11-01 | — | — | US | disclosed |
| US-6251963-B1 | ORGAOPHOSPHOROUS COMPOUND CONTAINING KETONE GROUP | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-06-26 | — | — | US | disclosed |