Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 14/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7618223 | 1.00 | TACR1 (0.54) | TACR1SIGMAR1CCR5TACR3MEN1 | |
| SCHEMBL8481125 | 0.88 | TACR1 (0.50) | TACR1CCR5TACR3MEN1KMT2A | |
| SCHEMBL8481128 | 0.88 | TACR1 (0.50) | TACR1CCR5TACR3MEN1KMT2A | |
| SCHEMBL7610397 | 0.85 | TACR1 (0.69) | TACR1TACR3 | |
| SCHEMBL7610403 | 0.85 | TACR1 (0.69) | TACR1TACR3 | |
| Acetic Acid SCHEMBL8525365 | 0.84 | TACR1 (0.54) | TACR1SIGMAR1TACR3 | |
| SCHEMBL7610359 | 0.84 | TACR1 (0.51) | TACR1SIGMAR1 | |
| SCHEMBL7610362 | 0.84 | TACR1 (0.51) | TACR1SIGMAR1 | |
| SCHEMBL8501936 | 0.83 | TACR1 (0.69) | TACR1TACR3 | |
| SCHEMBL8501940 | 0.83 | TACR1 (0.69) | TACR1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783490-B1 | 1-ACYL-4-ALIPHATIC AMINOPIPERIDINE COMPOUNDS | NOVARTIS AG (CH) | 2002-02-06 | — | — | EP | disclosed |
| US-5935951-A | ANTAGONIST AGAINST SUBSTANCE P | NOVARTIS FINANCE CORPORATION (US) | 1999-08-10 | — | — | US | disclosed |