Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 10/20 | 0.50 |
| ▸ | CHIT1 | Q13231 | 2/20 | 0.44 |
| ▸ | CHIA | Q9BZP6 | 2/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.41 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8481128 | 1.00 | TACR1 (0.50) | TACR1CHIT1CHIACCR5MEN1 | |
| SCHEMBL7618223 | 0.88 | TACR1 (0.54) | TACR1CCR5MEN1KMT2ATEAD1 | |
| SCHEMBL7618232 | 0.88 | TACR1 (0.54) | TACR1CCR5MEN1KMT2ATEAD1 | |
| SCHEMBL7610397 | 0.83 | TACR1 (0.69) | TACR1TACR3 | |
| SCHEMBL7610403 | 0.83 | TACR1 (0.69) | TACR1TACR3 | |
| SCHEMBL581154 | 0.82 | CHIT1 (0.43) | TACR1CHIT1CHIAOPRK1 | |
| SCHEMBL586739 | 0.82 | OPRK1 (0.50) | TACR1CHIT1CHIAMEN1KMT2A | |
| SCHEMBL8501936 | 0.81 | TACR1 (0.69) | TACR1TACR3 | |
| SCHEMBL8501940 | 0.81 | TACR1 (0.69) | TACR1TACR3 | |
| SCHEMBL8500474 | 0.81 | TACR1 (0.49) | TACR1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965562-A | TREATING DISORDERS INDUCED BY SUBSTANCE P AND MIGRAINE HEADACHE | NOVARTIS CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| US-5604247-A | NEUROKININE ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-02-18 | — | — | US | disclosed |