Isocoumarin

Isocoumarin

SCHEMBL76183

O=c1occc2ccccc12

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGES O14684 1/20 0.47
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
FTO Q9C0B1 1/20 0.45
ALDH1A1 P00352 5/20 0.43
TDP1 Q9NUW8 2/20 0.43
HSD17B10 Q99714 2/20 0.43
CYP2A6 P11509 1/20 0.43
TSHR P16473 1/20 0.43
PAX8 Q06710 1/20 0.43
CA1 P00915 1/20 0.42
CA9 Q16790 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
PARP1 P09874 1/20 0.40
HPRT1 P00492 1/20 0.40
ELANE P08246 2/20 0.38
MITF O75030 1/20 0.38
KMT2A Q03164 2/20 0.38
KDM4E B2RXH2 2/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isocoumarin SCHEMBL31031794 1.00 PTGES (0.47) PTGESMAOAMAOBFTOALDH1A1
Isocoumarin SCHEMBL27697885 0.98 PTGES (0.46) PTGESMAOAMAOBFTOALDH1A1
Isocoumarin SCHEMBL30855615 0.98 PTGES (0.46) PTGESMAOAMAOBFTOALDH1A1
Isocoumarin SCHEMBL29641549 0.98 PTGES (0.46) PTGESMAOAMAOBFTOALDH1A1
Isocoumarin SCHEMBL27513204 0.98 PTGES (0.46) PTGESMAOAMAOBFTOALDH1A1
Isocoumarin SCHEMBL28095716 0.98 PTGES (0.46) PTGESMAOAMAOBFTOALDH1A1
Isocoumarin SCHEMBL29641522 0.98 PTGES (0.46) PTGESMAOAMAOBFTOALDH1A1
Isocoumarin SCHEMBL5816683 0.96 PTGES (0.44) PTGESMAOAMAOBFTOALDH1A1
Isocoumarin SCHEMBL5816686 0.96 PTGES (0.44) PTGESMAOAMAOBFTOALDH1A1
Biphenyl SCHEMBL28466880 0.94 PTGES (0.52) PTGESMAOAMAOBFTOALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3356 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059625-A Mineral wool binder 洛科威有限公司 2026-05-19 CN claimed
CN-122029176-A Containing a plurality of oligonucleotides modified oligonucleotides 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 CN claimed
US-20260060970-A1 Use of a Therapeutic Agent with Phosphodiesterase-7 Inhibitory Activity for the Treatment and Prevention of Diseases Associated with Chronic Fatigue, Exhaustion and/or Exertional Intolerance MITODICURE GMBH (DE) 2026-03-05 US claimed
EP-4658641-A1 NOVEL COMPOUNDS THAT CAN BE USED AS THERAPEUTIC AGENTS Xeniom GmbH (DE) 2025-12-10 EP claimed
US-20250302678-A1 ABSORBENT ARTICLES INCLUDING PERFUME AND CYCLODEXTRINS PROCTER & GAMBLE (US) 2025-10-02 US claimed
US-12350136-B2 Absorbent articles including perfume and cyclodextrins THE PROCTER & GAMBLE COMPANY (US) 2025-07-08 US claimed
EP-4572765-A1 USE OF A THERAPEUTIC AGENT WITH PHOSPHODIESTERASE-7 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE Mitodicure GmbH (DE) 2025-06-25 EP claimed
US-20250161459-A1 TRKB LIGAND CONJUGATED COMPOUNDS AND USES THEREOF ADARX PHARMACEUTICALS, INC. (US) 2025-05-22 US claimed
EP-0368276-B1 Electrophotographic photoreceptor FUJI PHOTO FILM CO LTD (JP) 1994-02-02 EP claimed
US-5106712-A Sensitivity, durability FUJI PHOTO FILM CO., LTD. (JP) 1992-04-21 US claimed
US-5073465-A High sensitivity and durability FUJI PHOTO FILM CO., LTD. (JP) 1991-12-17 US claimed
US-5019474-A Containing tetrakisazo charge generating compound; high sensitivity, durability FUJI PHOTO FILM CO., LTD. (JP) 1991-05-28 US claimed
US-4977051-A CHARGE GENERATING, CHARGE TRANSFER COMPOUNDS FUJI PHOTO FILM CO., LTD. (JP) 1990-12-11 US claimed
EP-0399403-A1 Electrophotographic photoreceptor FUJI PHOTO FILM CO., LTD. (JP) 1990-11-28 EP claimed
EP-0391399-A1 Electrophotographic photoreceptor FUJI PHOTO FILM CO., LTD. (JP) 1990-10-10 EP claimed
EP-0368276-A2 Electrophotographic photoreceptor FUJI PHOTO FILM CO., LTD. (JP) 1990-05-16 EP claimed
US-4785097-A Method for synthesizing spiro-oxazines PPG INDUSTRIES, INC. (US) 1988-11-15 US claimed
US-4650881-A ONE POT IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 1987-03-17 US claimed