Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19113010 | 0.77 | — | — | |
| SCHEMBL15798070 | 0.75 | CYP2C19 (0.48) | CYP2C19CYP1A2ALDH1A1USP2LMNA | |
| Hydrochloric Acid SCHEMBL27856474 | 0.73 | CYP2C19 (0.47) | CYP2C19CYP1A2ALDH1A1USP2LMNA | |
| SCHEMBL8695790 | 0.73 | CYP2C19 (0.42) | CYP2C19CYP1A2ALDH1A1USP2LMNA | |
| SCHEMBL1825623 | 0.72 | CYP2C19 (0.45) | CYP2C19CYP1A2ALDH1A1USP2LMNA | |
| SCHEMBL27608123 | 0.72 | CYP2C19 (0.45) | CYP2C19CYP1A2ALDH1A1USP2LMNA | |
| SCHEMBL3369935 | 0.72 | CYP2C19 (0.45) | CYP2C19CYP1A2ALDH1A1USP2LMNA | |
| SCHEMBL5019821 | 0.71 | CYP2C19 (0.48) | CYP2C19CYP1A2ALDH1A1USP2LMNA | |
| SCHEMBL5608240 | 0.71 | CYP2C19 (0.48) | CYP2C19CYP1A2ALDH1A1USP2LMNA | |
| SCHEMBL3373260 | 0.69 | CYP2C19 (0.42) | CYP2C19CYP1A2ALDH1A1USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968178-B1 | N-SULPHONYL AND N-SULPHINYL AMINO ACID AMIDES AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-06-05 | — | — | EP | disclosed |
| US-6194463-B1 | SUCH AS ALPHA-(ETHYLSULFONYLAMINO)-CYCLOHEXANEACETIC ACID N-(2-(4-HYDROXY-3-METHOXYPHENYL)-ETHYL)-AMIDE; USE SUCH AS FOR CONTROLLING FUNGAL DISEASES IN CROPS | NOVARTIS CROP PROTECTION, INC. | 2001-02-27 | — | — | US | disclosed |
| EP-0968178-A1 | N-SULPHONYL AND N-SULPHINYL AMINO ACID AMIDES AS MICROBICIDES | Novartis AG (CH) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998038160-A1 | N-SULPHONYL AND N-SULPHINYL AMINO ACID AMIDES AS MICROBICIDES | NOVARTIS AG (CH) | 1998-09-03 | — | — | WO | disclosed |