Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.67 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene Diisocyanate SCHEMBL2054278 | 0.84 | CYP3A4 (0.83) | CYP3A4TRPA1MAPK1TDP1TSHR | |
| Toluene Diisocyanate SCHEMBL637112 | 0.82 | CYP3A4 (0.80) | CYP3A4TRPA1MAPK1TDP1TSHR | |
| Toluene Diisocyanate SCHEMBL27995911 | 0.82 | CYP3A4 (0.86) | CYP3A4TRPA1MAPK1TDP1TSHR | |
| Toluene Diisocyanate SCHEMBL19733056 | 0.82 | CYP3A4 (1.00) | CYP3A4TRPA1MAPK1TDP1TSHR | |
| Toluene Diisocyanate SCHEMBL29350148 | 0.82 | CYP3A4 (1.00) | CYP3A4TRPA1MAPK1TDP1TSHR | |
| Toluene Diisocyanate SCHEMBL15384 | 0.82 | CYP3A4 (1.00) | CYP3A4TRPA1MAPK1TDP1TSHR | |
| Toluene Diisocyanate SCHEMBL28174227 | 0.82 | CYP3A4 (1.00) | CYP3A4TRPA1MAPK1TDP1TSHR | |
| Toluene Diisocyanate SCHEMBL29737260 | 0.82 | CYP3A4 (1.00) | CYP3A4TRPA1MAPK1TDP1TSHR | |
| Toluene Diisocyanate SCHEMBL11209945 | 0.80 | CYP3A4 (0.96) | CYP3A4TRPA1MAPK1TDP1TSHR | |
| Toluene Diisocyanate SCHEMBL11825443 | 0.80 | CYP3A4 (0.96) | CYP3A4TRPA1MAPK1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945653-B | Electric viscous fluid and cylinder device | 日立安斯泰莫株式会社 | 2023-08-04 | — | — | CN | claimed |
| CN-111909340-A | High-temperature-resistant flame-retardant polyurethane composite material and preparation method thereof | 山东乐邦化工科技有限公司 | 2020-11-10 | — | — | CN | claimed |
| CN-107250196-B | Rigid polyurethane foams | 阿基里斯株式会社 | 2020-05-12 | — | — | CN | claimed |
| US-3948941-A | NITRILE, FROM CARBOXYLIC ANHYDRIDES AND ISOCYANATES | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1976-04-06 | — | — | US | claimed |
| JP-3200829-A | — | — | None | — | — | JP | disclosed |
| CN-116789924-A | High-strength flame-retardant flexible polyurethane foam material and preparation method thereof | 江苏米尔化工科技有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-114945653-B | Electric viscous fluid and cylinder device | 日立安斯泰莫株式会社 | 2023-08-04 | — | — | CN | disclosed |
| CN-114945653-A | Electroviscous fluid and cylinder device | 日立安斯泰莫株式会社 | 2022-08-26 | — | — | CN | disclosed |
| CN-111909340-A | High-temperature-resistant flame-retardant polyurethane composite material and preparation method thereof | 山东乐邦化工科技有限公司 | 2020-11-10 | — | — | CN | disclosed |
| CN-111909340-A | High-temperature-resistant flame-retardant polyurethane composite material and preparation method thereof | 山东乐邦化工科技有限公司 | 2020-11-10 | — | — | CN | disclosed |
| EP-0983309-B1 | PROCESS FOR PREPARING POLYURETHANE FOAMS | KRATON POLYMERS RES BV (NL) | 2002-07-24 | — | — | EP | disclosed |
| EP-0983309-A1 | POLYURETHANE FOAMS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 2000-03-08 | — | — | EP | disclosed |
| US-5973016-A | A POLYURETHANE FOAM COMPRISES HYDROGENATED POLYDIENE DIOL; AND AROMATIC POLYISOCYANATE; OIL; AND WATER AS BLOWING AGENT; EXCELLENT PROCESSABILITY | SHELL OIL COMPANY (US) | 1999-10-26 | — | — | US | disclosed |
| US-5922781-A | FROM A POLYDIENE DIOL | SHELL OIL COMPANY (US) | 1999-07-13 | — | — | US | disclosed |
| US-5849806-A | Resilient polyurethane foams of polydiene diols and tackifying resin | SHELL OIL COMPANY (US) | 1998-12-15 | — | — | US | disclosed |
| WO-1998052986-A1 | POLYURETHANE FOAMS | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1998-11-26 | — | — | WO | disclosed |
| WO-1998052987-A1 | POLYURETHANE FOAMS | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1998-11-26 | — | — | WO | disclosed |
| US-5115072-A | Polycarbodiimides | REICHHOLD CHEMICALS, INC. (US) | 1992-05-19 | — | — | US | disclosed |
| JP-H03200829-A | PRODUCTION OF FLEXIBLE ELASTIC POLYURETHANE FOAM | MITSUI TOATSU CHEM INC | 1991-09-02 | — | — | JP | disclosed |
| EP-0148576-A1 | High resiliency molded urethane foams containing high levels of graft copolymer polyols | DOW CORNING CORPORATION (US) | 1985-07-17 | — | — | EP | disclosed |