Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 11/20 | 0.54 |
| ▸ | C5 | P01031 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | EBP | Q15125 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6898088 | 0.84 | MCHR1 (0.67) | MCHR1HTR2C | |
| SCHEMBL6901278 | 0.82 | MCHR1 (0.60) | MCHR1HTR2C | |
| SCHEMBL6921907 | 0.82 | MCHR1 (0.80) | MCHR1HTR2C | |
| SCHEMBL6896989 | 0.82 | MCHR1 (0.67) | MCHR1HTR2C | |
| SCHEMBL7609714 | 0.81 | MCHR1 (0.49) | MCHR1C5SIGMAR1EBPTMEM97 | |
| SCHEMBL6899005 | 0.81 | MCHR1 (0.63) | MCHR1HTR2C | |
| SCHEMBL6892162 | 0.81 | MCHR1 (0.71) | MCHR1HTR2C | |
| SCHEMBL6895401 | 0.80 | MCHR1 (0.70) | MCHR1HTR2C | |
| SCHEMBL6899096 | 0.80 | MCHR1 (0.70) | MCHR1SIGMAR1EBPTMEM97HTR2C | |
| SCHEMBL6899460 | 0.80 | MCHR1 (0.62) | MCHR1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100495-A4 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORP (US) | 2002-09-25 | — | — | EP | claimed |
| JP-2002521441-A | — | — | 2002-07-16 | — | — | JP | claimed |
| EP-1100495-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-23 | — | — | EP | claimed |
| WO-2000006153-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | claimed |
| EP-1100495-A4 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORP (US) | 2002-09-25 | — | — | EP | disclosed |
| EP-1100495-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000006153-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | disclosed |