Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 18/20 | 0.55 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7643915 | 0.92 | PLA2G1B (0.48) | PLA2G1BPLA2G2A | |
| SCHEMBL7189199 | 0.84 | PLA2G1B (0.64) | PLA2G1BPLA2G2A | |
| SCHEMBL7645569 | 0.83 | PLA2G1B (0.55) | PLA2G1BPLA2G2A | |
| SCHEMBL7185931 | 0.77 | PLA2G1B (0.56) | PLA2G1BPLA2G2A | |
| SCHEMBL7621908 | 0.75 | PLA2G1B (0.49) | PLA2G1BPLA2G2A | |
| SCHEMBL7616781 | 0.74 | PLA2G1B (0.47) | PLA2G1BPLA2G2A | |
| SCHEMBL7641632 | 0.73 | PLA2G1B (0.54) | PLA2G1BPLA2G2A | |
| SCHEMBL7647147 | 0.72 | PLA2G1B (0.55) | PLA2G1BPLA2G2A | |
| SCHEMBL7643254 | 0.71 | PLA2G1B (0.52) | PLA2G1BPLA2G2A | |
| SCHEMBL7015420 | 0.71 | PLA2G1B (0.85) | PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265607-A2 | METHOD FOR THE TREATMENT OF RENAL DYSFUNCTION WITH sPLA 2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001066110-A2 | METHOD FOR THE TREATMENT OF RENAL DYSFUNCTION WITH sPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-09-13 | — | — | WO | disclosed |