Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 6/20 | 0.52 |
| ▸ | TYMP | P19971 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615989 | 1.00 | SLC29A1 (0.52) | SLC29A1TYMPADORA2AADORA2BADORA3 | |
| SCHEMBL8914132 | 0.91 | SLC29A1 (0.43) | SLC29A1TYMPADORA2AADORA2B | |
| SCHEMBL8912999 | 0.88 | SLC29A1 (0.40) | SLC29A1TYMPADORA2AADORA2B | |
| SCHEMBL7756536 | 0.85 | TYMP (0.46) | SLC29A1TYMP | |
| SCHEMBL7710522 | 0.85 | SLC29A1 (0.40) | SLC29A1TYMPADORA2AADORA2BADORA3 | |
| SCHEMBL13057654 | 0.84 | TYMP (0.51) | TYMPADORA2AADORA2BADORA3 | |
| SCHEMBL18496453 | 0.84 | TYMP (0.51) | TYMPADORA2AADORA2BADORA3 | |
| SCHEMBL1069795 | 0.82 | ADORA2B (0.49) | TYMPADORA2AADORA2BADORA3 | |
| SCHEMBL3796393 | 0.82 | ADORA2B (0.49) | TYMPADORA2AADORA2BADORA3 | |
| SCHEMBL1068391 | 0.77 | TYMP (0.55) | TYMPNT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630249-B1 | DUAL ACTION 2',5'-OLIGOADENYLATE ANTIVIRAL DERIVATIVES AND USES THEREOF | UNIV TEMPLE (US) | 2002-09-18 | — | — | EP | disclosed |
| WO-1993017692-A1 | DUAL ACTION 2',5'-OLIGOADENYLATE ANTIVIRAL DERIVATIVES AND USES THEREOF | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1993-09-16 | — | — | WO | disclosed |