Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7620268 | 0.99 | KMT2A (0.47) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7655442 | 0.99 | KMT2A (0.47) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7244570 | 0.92 | KMT2A (0.52) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7616016 | 0.91 | KMT2A (0.47) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7243072 | 0.91 | KMT2A (0.51) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7250194 | 0.86 | KMT2A (0.53) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7614697 | 0.83 | PPARG (0.41) | KMT2AMEN1ALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL7618948 | 0.82 | PPARG (0.49) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7250273 | 0.81 | KMT2A (0.53) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6744201 | 0.80 | KMT2A (0.69) | KMT2AMEN1ALDH1A1LMNAGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495701-B1 | THE PRESENT INVENTION IS DIRECTED TO PROCESSES FOR THE PREPARATION OF A COMPOUND USEFUL FOR TREATING DIABETES, OBESITY, HYPERLIPIDEMIA AND THE LIKE, | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-12-17 | — | — | US | disclosed |
| EP-1174425-A1 | NOVEL METHOD FOR MANUFACTURING TRICYCLIC AMINO ALCOHOL DERIVATIVES | Asahi Kasei Kabushiki Kaisha (JP) | 2002-01-23 | — | — | EP | disclosed |