Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7618868 | 0.93 | ACHE (0.42) | PPARGALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7618948 | 0.89 | PPARG (0.49) | PPARGALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7620186 | 0.86 | EGFR (0.43) | ALDH1A1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL7531469 | 0.84 | MEN1 (0.43) | ALDH1A1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL7619230 | 0.83 | KMT2A (0.47) | PPARGALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6744892 | 0.83 | KMT2A (0.56) | ALDH1A1MEN1KMT2AL3MBTL1CNR2 | |
| Bromide SCHEMBL7620268 | 0.83 | KMT2A (0.47) | PPARGALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7655442 | 0.83 | KMT2A (0.47) | PPARGALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7615925 | 0.81 | PPARG (0.49) | PPARGALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7244095 | 0.79 | MAOB (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495701-B1 | THE PRESENT INVENTION IS DIRECTED TO PROCESSES FOR THE PREPARATION OF A COMPOUND USEFUL FOR TREATING DIABETES, OBESITY, HYPERLIPIDEMIA AND THE LIKE, | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-12-17 | — | — | US | disclosed |
| EP-1174425-A1 | NOVEL METHOD FOR MANUFACTURING TRICYCLIC AMINO ALCOHOL DERIVATIVES | Asahi Kasei Kabushiki Kaisha (JP) | 2002-01-23 | — | — | EP | disclosed |