Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | CPA1 | P15085 | 1/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 5/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615764 | 0.87 | KMT2A (0.58) | KMT2AMMEACECPA1ACE2 | |
| SCHEMBL3149585 | 0.83 | KMT2A (0.71) | KMT2AMMEACECPA1ACE2 | |
| SCHEMBL23189270 | 0.83 | KMT2A (0.71) | KMT2AMMEACECPA1ACE2 | |
| Bicarbonate SCHEMBL27541289 | 0.81 | KMT2A (0.68) | KMT2AMMEACECPA1ACE2 | |
| SCHEMBL9148917 | 0.80 | KMT2A (1.00) | KMT2AMMEACECPA1ACE2 | |
| SCHEMBL6129897 | 0.78 | PPARG (0.50) | NR4A2PPARAPPARGSLC6A2SLC6A4 | |
| SCHEMBL5610692 | 0.77 | KMT2A (0.61) | KMT2AMMEACECPA1ACE2 | |
| SCHEMBL5272384 | 0.77 | KMT2A (0.61) | KMT2AMMEACECPA1ACE2 | |
| SCHEMBL17523029 | 0.77 | NR4A2 (0.43) | KMT2AACENR4A2FOLH1 | |
| SCHEMBL29238353 | 0.77 | KMT2A (0.67) | KMT2AMMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834519-B1 | CATALYST FOR POLYOLEFIN PRODUCTION AND PROCESS FOR PRODUCING POLYOLEFIN | JAPAN POLYOLEFINS CO LTD (JP) | 2002-03-06 | — | — | EP | disclosed |
| US-6121182-A | A METALLOCENE CATALYST FOR POLYMERIZATION OF ISOTACTIC POLYOLEFINS WITH HIGH RIGIDITY AND HIGH MELTING POINT, USEFUL AS INDUSTRIAL MATERIAL FOR AUTOMOBILES | JAPAN POLYOLAFINS CO., LTD. (JP) | 2000-09-19 | — | — | US | disclosed |
| EP-0834519-A1 | CATALYST FOR POLYOLEFIN PRODUCTION AND PROCESS FOR PRODUCING POLYOLEFIN | Japan Polyolefins Co., Ltd. (JP) | 1998-04-08 | — | — | EP | disclosed |