Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.61 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.61 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.61 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.61 |
| ▸ | MME | P08473 | 3/20 | 0.53 |
| ▸ | ACE | P12821 | 3/20 | 0.53 |
| ▸ | CPA1 | P15085 | 1/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23189270 | 1.00 | KMT2A (0.71) | KMT2APTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL17051298 | 0.86 | KMT2A (0.51) | KMT2APTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8520662 | 0.85 | APAF1 (0.59) | KMT2APTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3141425 | 0.84 | PTGER1 (0.54) | KMT2APTGER1PTGER4PTGER3PTGER2 | |
| Bicarbonate SCHEMBL27541289 | 0.84 | KMT2A (0.68) | KMT2APTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL9148917 | 0.83 | KMT2A (1.00) | KMT2APTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3158742 | 0.83 | PTGER1 (0.56) | KMT2APTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL7619239 | 0.83 | KMT2A (0.67) | KMT2APTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL9357720 | 0.82 | KMT2A (0.57) | KMT2APTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3157543 | 0.81 | PTGER1 (0.48) | KMT2APTGER1PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116678-B | Dinuclear metallocene compound and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-111116788-B | Polypropylene and preparation method thereof | 中国石油化工股份有限公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-111116789-B | Binuclear metallocene supported catalyst and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-111116678-A | Dinuclear metallocene compound and preparation method and application thereof | 中国石油化工股份有限公司 | 2020-05-08 | — | — | CN | disclosed |
| CN-111116789-A | Binuclear metallocene supported catalyst and preparation method and application thereof | 中国石油化工股份有限公司 | 2020-05-08 | — | — | CN | disclosed |
| CN-111116788-A | Polypropylene and preparation method thereof | 中国石油化工股份有限公司 | 2020-05-08 | — | — | CN | disclosed |
| US-9163046-B2 | Process for producing substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-10-20 | — | — | US | disclosed |
| US-20100113717-A1 | Process For Producing Substituted Metallocene Compounds For Olefin Polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2010-05-06 | — | — | US | disclosed |
| US-7709670-B2 | Process for producing substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-05-04 | — | — | US | disclosed |
| EP-1866322-B1 | PROCESS FOR PRODUCING SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2010-02-24 | — | — | EP | disclosed |
| US-5770753-A | ADDITION POLYMERIZATION CATALYST | TARGOR GMBH (DE) | 1998-06-23 | — | — | US | disclosed |
| EP-0705281-B1 | SUPPORTED METALLOCENE CATALYST SYSTEMS FOR THE POLYMERIZATION OF OLEFINS, PREPARATION AND USE THEREOF | EXXON CHEMICAL PATENTS INC (US) | 1998-03-11 | — | — | EP | disclosed |
| EP-0576970-B1 | Metallocenes with arylsubstituted indenyl-derivatives as ligands, process for their preparation and their use as catalysts | HOECHST AG (DE) | 1998-01-14 | — | — | EP | disclosed |
| EP-0790076-A2 | Catalysts containing metallocenes with arylsubstituted indenyl derivatives as ligands, process and intermediates for the preparation of these metallocenes and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-08-20 | — | — | EP | disclosed |
| EP-0776913-A2 | High molecular weight copolymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-04 | — | — | EP | disclosed |
| CN-1130912-A | Supported metallocene catalyst systems for polymerization of olefins, preparation and use thereof | EXXON CHEMICAL PATENTS INC (US) | 1996-09-11 | — | — | CN | disclosed |
| EP-0470832-B1 | Biphenyl 5,5'-bis-alkanoic acid derivatives, their production and use thereof | ASAHI CHEMICAL IND (JP) | 1994-12-14 | — | — | EP | disclosed |
| EP-0576970-A1 | Metallocenes with arylsubstituted indenyl-derivatives as ligands, process for their preparation and their use as catalysts | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-01-05 | — | — | EP | disclosed |
| US-5136090-A | Antidiabetic agents | TOYO JOZO KABUSHIKI KAISHA (JP) | 1992-08-04 | — | — | US | disclosed |
| EP-0470832-A2 | Biphenyl 5,5'-bis-alkanoic acid derivatives, their production and use thereof | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1992-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113717-A1 | Process For Producing Substituted Metallocene Compounds For Olefin Polymerization | OSBP, OSBPL3, OSBP2 | KMT2A 3398/4885PTGER1 4249/4885PTGER4 1617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.