SCHEMBL7619684

SCHEMBL7619684

CCOc1cccc(-c2nc3ccccc3s2)c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.72
SMN1; SMN2 Q16637 7/20 0.72
RAB9A P51151 6/20 0.72
NFKB1 P19838 3/20 0.72
NFKB2 Q00653 3/20 0.72
RELA Q04206 3/20 0.72
TDP1 Q9NUW8 2/20 0.72
KDM4E B2RXH2 7/20 0.63
NPC1 O15118 5/20 0.63
KMT2A Q03164 3/20 0.63
GLA P06280 1/20 0.63
MEN1 O00255 2/20 0.59
ALDH1A1 P00352 2/20 0.59
HPGD P15428 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
TP53 P04637 3/20 0.57
LMNA P02545 2/20 0.57
POLB P06746 2/20 0.57
HSD17B10 Q99714 1/20 0.57
NOTUM Q6P988 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15462906 0.88 MAPT (0.67) MAPTSMN1; SMN2RAB9ANFKB1NFKB2
SCHEMBL14743620 0.84 MAPT (0.63) MAPTSMN1; SMN2RAB9ANFKB1NFKB2
SCHEMBL13198328 0.84 KDM4E (0.70) MAPTSMN1; SMN2RAB9ATDP1KDM4E
SCHEMBL2090795 0.84 MAPT (1.00) MAPTSMN1; SMN2RAB9ANFKB1NFKB2
SCHEMBL30161523 0.84 MAPT (1.00) MAPTSMN1; SMN2RAB9ANFKB1NFKB2
SCHEMBL29474943 0.84 SMN1; SMN2 (0.65) MAPTSMN1; SMN2RAB9ANFKB1NFKB2
SCHEMBL12470981 0.84 RAB9A (0.65) MAPTSMN1; SMN2RAB9ANFKB1NFKB2
SCHEMBL8361595 0.82 KMT2A (0.61) MAPTSMN1; SMN2RAB9ANFKB1NFKB2
SCHEMBL14742582 0.82 FFAR1 (0.71) MAPTSMN1; SMN2RAB9ANFKB1NFKB2
SCHEMBL2090792 0.81 RAB9A (0.74) MAPTSMN1; SMN2RAB9ANFKB1NFKB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012104875-A1 BENZOTHIAZOLE HYBRIDS USEFUL AS ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2012-08-09 WO disclosed
EP-0915370-B1 Silver halide light-sensitive photographic material KONISHIROKU PHOTO IND (JP) 2002-03-13 EP disclosed
US-6174658-B1 IMAGE SHARPNESS, WHIENESS AND BRIGHTNESS KONICA CORPORATION (JP) 2001-01-16 US disclosed
EP-0562476-B1 Method for preparing a silver halide photographic emulsion FUJI PHOTO FILM CO LTD (JP) 2000-10-04 EP disclosed
US-6068968-A CYANINE DYE HAVING AT LEAST ONE SUBSTITUENT HAVING A THIOETHER GROUP; EXHIBITING LOW FOGGING, HIGH SENSITIVITY, AND IMPROVED STORAGE STABILITY. FUJI PHOTO FILM CO., LTD. (JP) 2000-05-30 US disclosed
US-6027870-A INFRARED-SENSITIVE PHOTOTHERMOGRAPHIC MATERIAL CONTAINING A CYANINE DYE; STORAGE STABILITY, ANTIFOGGING AGENTS FUJI PHOTO FILM CO., LTD. (JP) 2000-02-22 US disclosed
EP-0565121-B1 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1999-07-14 EP disclosed
EP-0915370-A1 Silver halide light-sensitive photographic material KONICA CORPORATION (JP) 1999-05-12 EP disclosed
EP-0534283-B1 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1997-12-17 EP disclosed
US-5691125-A CYAN DYE-FORMING COUPLER, STORAGE STABLE FUJI PHOTO FILM CO., LTD. (JP) 1997-11-25 US disclosed
EP-0314104-B1 SILVER HALIDE PHOTOGRAPHIC MATERIALS FUJI PHOTO FILM CO., LTD. (JP) 1993-09-15 EP disclosed
EP-0534283-A2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1993-03-31 EP disclosed
US-5093222-A Contrast, negatives FUJI PHOTO FILM CO., LTD. (JP) 1992-03-03 US disclosed
EP-0452811-A2 Package of photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1991-10-23 EP disclosed
US-5015561-A Method for forming a direct positive image FUJI PHOTO FILM CO., LTD. (JP) 1991-05-14 US disclosed
US-4971889-A Spectral sensitizing dye containnig a hydrazine residue FUJI PHOTO FILM CO., LTD. (JP) 1990-11-20 US disclosed
US-4943515-A RADIATING A SUBSTRATE-SUPPORTED RECORDING LAYER COMPRISING AN ORGANIC SOLVENT-SOLUBLE SILVER SALT AND A DYE WITH A LASER BEAM FUJI PHOTO FILM CO., LTD. (JP) 1990-07-24 US disclosed
EP-0357082-A2 Silver halide photographic emulsions FUJI PHOTO FILM CO., LTD. (JP) 1990-03-07 EP disclosed
EP-0314104-A2 Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1989-05-03 EP disclosed
US-4800154-A SPECTRAL SENSITIZINY CYANINE, MEROCYANINE, STYRYL AND OXONOL DYES FUJI PHOTO FILM CO., LTD. (JP) 1989-01-24 US disclosed