Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CPT2 | P23786 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7614010 | 0.98 | TSHR (0.36) | ACLYACACBACACATSHRALDH1A1 | |
| SCHEMBL9620660 | 0.90 | ACLY (0.43) | ACLYACACBACACATSHRALDH1A1 | |
| SCHEMBL9620785 | 0.90 | ACLY (0.43) | ACLYACACBACACATSHRALDH1A1 | |
| SCHEMBL9060464 | 0.90 | ACLY (0.43) | ACLYACACBACACATSHRALDH1A1 | |
| SCHEMBL9620360 | 0.90 | ACLY (0.43) | ACLYACACBACACATSHRALDH1A1 | |
| SCHEMBL9620703 | 0.87 | TSHR (0.44) | ACLYACACBACACATSHRALDH1A1 | |
| SCHEMBL11386150 | 0.79 | — | — | |
| SCHEMBL7618722 | 0.79 | ACLY (0.45) | ACLYACACBACACATSHRALDH1A1 | |
| SCHEMBL10869000 | 0.79 | ACLY (0.61) | ACLYACACBACACATSHRFFAR1 | |
| SCHEMBL10872185 | 0.79 | ACLY (0.61) | ACLYACACBACACATSHRFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790824-B1 | 2,2-DICHLOROALKANE CARBOXYLIC ACIDS, PROCESS FOR PREPARING THE SAME, MEDICAMENT CONTAINING THE SAME, AND USE THEREOF FOR TREATING INSULIN RESISTANCE | ROCHE DIAGNOSTICS GMBH (DE) | 2002-02-06 | — | — | EP | disclosed |
| US-5968982-A | TREATMENT OF DIABETES | ROCHE DIAGNOSTICS GMBH (DE) | 1999-10-19 | — | — | US | disclosed |