Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7617432 | 0.79 | NPC1 (0.38) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL25206705 | 0.76 | ALOX15 (0.53) | KMT2AMEN1ALDH1A1POLBKDM4E | |
| SCHEMBL6015974 | 0.75 | CYP1A2 (0.38) | KMT2AMEN1AURKAPARP1CYP1A2 | |
| SCHEMBL29955300 | 0.73 | KMT2A (0.44) | KMT2AMEN1AURKAPARP1ALDH1A1 | |
| SCHEMBL1714222 | 0.70 | KMT2A (0.47) | KMT2AMEN1AURKAPARP1ALDH1A1 | |
| SCHEMBL7990805 | 0.69 | MAP2K1 (0.50) | KMT2AMEN1AURKAPARP1CYP1A2 | |
| SCHEMBL7965933 | 0.68 | KMT2A (0.45) | KMT2AMEN1AURKAPARP1ALDH1A1 | |
| SCHEMBL2345339 | 0.68 | KMT2A (0.47) | KMT2AMEN1AURKAPARP1ALDH1A1 | |
| SCHEMBL1777902 | 0.67 | HDAC1 (0.44) | KMT2AMEN1AURKAPARP1ALDH1A1 | |
| SCHEMBL3260360 | 0.66 | MAP2K1 (0.49) | KMT2AMEN1AURKAPARP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | disclosed |