Sugi Predict

Sugi Predict / Compounds / SCHEMBL7619980

SCHEMBL7619980

SCHEMBL7619980

CO[C@H]1[C@H](O)[C@@H](CO)O[C@H]1[C@]1(n2cc(C)c(=O)[nH]c2=O)C[C@H](O)[C@@H](CO)O1

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ TK2 O00142 2/20 0.41
▸ TK1 P04183 7/20 0.39
▸ TYMP P19971 1/20 0.36
▸ ALB P02768 1/20 0.36
▸ PKM P14618 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5036896 0.89 TK1 (0.41) TK2TK1ALB
SCHEMBL9060459 0.89 TK1 (0.41) TK2TK1ALB
SCHEMBL7027956 0.82 TK1 (0.39) TK1ALBPKM
SCHEMBL7033423 0.82 TK1 (0.39) TK1ALBPKM
SCHEMBL29474410 0.82 TK1 (0.39) TK1ALBPKM
SCHEMBL29088052 0.82 TK1 (0.39) TK1ALBPKM
SCHEMBL29763091 0.82 TK1 (0.39) TK1ALBPKM
SCHEMBL5698865 0.82 TK1 (0.39) TK1ALBPKM
SCHEMBL29276434 0.81 TK1 (0.50) TK1
SCHEMBL31074821 0.79 TK1 (0.44) TK2TK1ALBPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1222309-A4 HUMAN RNASE H AND OLIGONUCLEOTIDE COMPOSITIONS THEREOF ISIS PHARMACEUTICALS INC (US) 2002-12-04 — — EP disclosed
EP-1222309-A1 HUMAN RNASE H AND OLIGONUCLEOTIDE COMPOSITIONS THEREOF ISIS PHARMACEUTICALS, INC. (US) 2002-07-17 — — EP disclosed
WO-2001023613-A1 HUMAN RNASE H AND OLIGONUCLEOTIDE COMPOSITIONS THEREOF ISIS PHARMACEUTICALS, INC. (US) 2001-04-05 — — WO disclosed