Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 10/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 8/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.34 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.32 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.32 |
| ▸ | GPR183 | P32249 | 1/20 | 0.32 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.32 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7621724 | 0.85 | ACACB (0.35) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL7620027 | 0.82 | S1PR1 (0.44) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| Hydrochloric Acid SCHEMBL7615564 | 0.79 | CYP2D6 (0.41) | — | |
| SCHEMBL7615631 | 0.78 | S1PR1 (0.40) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL7620008 | 0.74 | S1PR1 (0.56) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL7620681 | 0.73 | S1PR1 (0.39) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL7614927 | 0.72 | S1PR1 (0.46) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL8498832 | 0.68 | S1PR1 (0.48) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL4917300 | 0.68 | S1PR1 (0.48) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL8529514 | 0.68 | S1PR1 (0.48) | S1PR1S1PR4S1PR3S1PR5S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778263-B1 | BENZENE COMPOUND AND MEDICINAL USE THEREOF | WELFIDE CORP (JP) | 2002-01-09 | — | — | EP | disclosed |