Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 11/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 9/20 | 0.56 |
| ▸ | S1PR4 | O95977 | 7/20 | 0.56 |
| ▸ | TNNC1 | P63316 | 6/20 | 0.56 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.56 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.56 |
| ▸ | GPR183 | P32249 | 1/20 | 0.56 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.56 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7620027 | 0.88 | S1PR1 (0.44) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| SCHEMBL7615930 | 0.81 | S1PR1 (0.63) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| SCHEMBL7613362 | 0.80 | S1PR1 (0.62) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| SCHEMBL12314891 | 0.78 | S1PR1 (0.69) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| SCHEMBL7621724 | 0.77 | ACACB (0.35) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| SCHEMBL7614950 | 0.77 | S1PR1 (0.88) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| Hydrochloric Acid SCHEMBL7713904 | 0.76 | S1PR1 (0.88) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| SCHEMBL7615664 | 0.74 | S1PR1 (0.63) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| SCHEMBL7622031 | 0.74 | S1PR1 (0.63) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| Fingolimod SCHEMBL7445 | 0.74 | S1PR1 (1.00) | S1PR1S1PR3S1PR4TNNC1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372800-B1 | IMMUNOSUPPRESSIVE EFFECT AND IS USEFUL AS AN INHIBITOR FOR THE REJECTION REACTION OCCURRING IN ORGAN OR BONE MARROW TRANSPLANTATION, AND AS A PREVENTIVE OR REMEDY FOR ARTICULAR RHEUMATISM, ATOPIC ECZEMA (DERMATITIS), BEHCET'S DISEASE, | MITSUBISHI PHARMA CORPORATION (JP) | 2002-04-16 | — | — | US | disclosed |
| EP-0778263-B1 | BENZENE COMPOUND AND MEDICINAL USE THEREOF | WELFIDE CORP (JP) | 2002-01-09 | — | — | EP | disclosed |
| US-6187821-B1 | SUCH AS 2-AMINO-2-(3-(4-HEPTYLPHENYL)PROPYL)BUTANE-1,4-DIOL; IMMUNOSUPPRESSANT; ADMINISTERING TO TREAT OR PREVENT AUTOIMMUNE DISEASES AND ALLERGIES | WELFIDE CORPORATION (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0778263-A1 | BENZENE COMPOUND AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-11 | — | — | EP | disclosed |