Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 15/20 | 0.81 |
| ▸ | DRD5 | P21918 | 5/20 | 0.81 |
| ▸ | DRD2 | P14416 | 8/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.64 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.64 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.64 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.64 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.64 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.64 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.64 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.64 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | THPO | P40225 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7621209 | 1.00 | DRD1 (0.81) | DRD1DRD5DRD2KDM4EHPGD | |
| SCHEMBL7320752 | 1.00 | DRD1 (0.81) | DRD1DRD5DRD2KDM4EHPGD | |
| SCHEMBL11710309 | 0.92 | DRD1 (0.73) | DRD1DRD5DRD2KDM4EHPGD | |
| SCHEMBL10745206 | 0.90 | DRD1 (0.74) | DRD1DRD5DRD2KDM4EHPGD | |
| SCHEMBL11103715 | 0.90 | DRD1 (0.70) | DRD1DRD5DRD2KDM4EHPGD | |
| SCHEMBL11103721 | 0.90 | DRD1 (0.70) | DRD1DRD5DRD2KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL10748542 | 0.90 | DRD1 (0.70) | DRD1DRD5DRD2KDM4EHPGD | |
| SCHEMBL11103719 | 0.90 | DRD1 (0.70) | DRD1DRD5DRD2KDM4EHPGD | |
| SCHEMBL10345411 | 0.90 | DRD1 (0.70) | DRD1DRD5DRD2KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL10745319 | 0.89 | DRD1 (0.69) | DRD1DRD5DRD2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020019389-A1 | Urea derivative useful as an anti-cancer agent and process for preparing same | CHACONNE NSI CO., LTD. (KR) | 2002-02-14 | — | — | US | disclosed |
| EP-1083893-A1 | MULTIVALENT AGONISTS, PARTIAL AGONISTS, INVERSE AGONISTS AND ANTAGONISTS OF THE D 1? RECEPTORS | Advanced Medicine, Inc. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999063993-A1 | MULTIVALENT AGONISTS, PARTIAL AGONISTS, INVERSE AGONISTS AND ANTAGONISTS OF THE D1 RECEPTORS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019389-A1 | Urea derivative useful as an anti-cancer agent and process for preparing same | UTS2R, SLC14A1, URB2 | DRD1 3415/4885DRD5 3091/4885DRD2 4158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.