Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.62 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | F7 | P08709 | 5/20 | 0.46 |
| ▸ | F3 | P13726 | 5/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | PPARD | Q03181 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | FABP3 | P05413 | 3/20 | 0.46 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7625796 | 1.00 | KDM4E (0.62) | KDM4ESOAT1CNR1CYP3A4MEN1 | |
| SCHEMBL7621800 | 1.00 | KDM4E (0.62) | KDM4ESOAT1CNR1CYP3A4MEN1 | |
| SCHEMBL7621344 | 0.95 | FAAH (0.59) | KDM4ESOAT1CNR1CYP3A4MEN1 | |
| SCHEMBL7620605 | 0.95 | FAAH (0.59) | KDM4ESOAT1CNR1CYP3A4MEN1 | |
| SCHEMBL7622255 | 0.95 | FAAH (0.59) | KDM4ESOAT1CNR1CYP3A4MEN1 | |
| SCHEMBL7623434 | 0.95 | FAAH (0.59) | KDM4ESOAT1CNR1CYP3A4MEN1 | |
| SCHEMBL7619344 | 0.95 | FAAH (0.59) | KDM4ESOAT1CNR1CYP3A4MEN1 | |
| SCHEMBL7620597 | 0.95 | FAAH (0.59) | KDM4ESOAT1CNR1CYP3A4MEN1 | |
| SCHEMBL7629370 | 0.95 | FAAH (0.59) | KDM4ESOAT1CNR1CYP3A4MEN1 | |
| SCHEMBL7624105 | 0.95 | FAAH (0.59) | KDM4ESOAT1CNR1CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444832-B1 | OSTEOPOROSIS | ESSWEIN ANGELIKA (DE) | 2002-09-03 | — | — | US | disclosed |
| EP-0865422-B1 | USE OF AMINOALCOHOLDERIVATIVES AS DRUGS, DERIVATIVES AND PROCESS FOR THEIR PREPARATION | ROCHE DIAGNOSTICS GMBH (DE) | 2001-07-11 | — | — | EP | disclosed |