Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 1/20 | 0.63 |
| ▸ | CNR1 | P21554 | 1/20 | 0.62 |
| ▸ | CETP | P11597 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CNR2 | P34972 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.56 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14010922 | 1.00 | DEGS1 (0.63) | DEGS1CNR1CETPTHRBMEN1 | |
| SCHEMBL7619349 | 1.00 | DEGS1 (0.63) | DEGS1CNR1CETPTHRBMEN1 | |
| SCHEMBL7621349 | 1.00 | DEGS1 (0.63) | DEGS1CNR1CETPTHRBMEN1 | |
| SCHEMBL7622257 | 1.00 | DEGS1 (0.63) | DEGS1CNR1CETPTHRBMEN1 | |
| SCHEMBL7620608 | 0.97 | CNR1 (0.59) | DEGS1CNR1CETPTHRBMEN1 | |
| SCHEMBL7623440 | 0.97 | CNR1 (0.59) | DEGS1CNR1CETPTHRBMEN1 | |
| SCHEMBL14199487 | 0.96 | CNR1 (0.69) | DEGS1CNR1THRBMEN1KMT2A | |
| SCHEMBL2168034 | 0.94 | DEGS1 (0.66) | DEGS1CNR1CETPTHRBMEN1 | |
| SCHEMBL2168031 | 0.94 | DEGS1 (0.66) | DEGS1CNR1CETPTHRBMEN1 | |
| SCHEMBL2058960 | 0.92 | FAAH (0.60) | DEGS1CETPTHRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444832-B1 | OSTEOPOROSIS | ESSWEIN ANGELIKA (DE) | 2002-09-03 | — | — | US | disclosed |