Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.55 |
| ▸ | PPARG | P37231 | 13/20 | 0.55 |
| ▸ | PPARD | Q03181 | 6/20 | 0.53 |
| ▸ | PTGES | O14684 | 4/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818192 | 0.89 | PPARG (0.47) | PPARAPPARGPPARDFFAR1LMNA | |
| SCHEMBL7247920 | 0.82 | PPARG (0.56) | PPARAPPARGPPARDPTGESALOX5 | |
| SCHEMBL5991810 | 0.81 | PPARG (0.55) | PPARAPPARGPPARDPTGESALOX5 | |
| SCHEMBL28441594 | 0.80 | PPARA (0.62) | PPARAPPARGPPARDALOX5FFAR1 | |
| SCHEMBL6821634 | 0.79 | FFAR1 (0.40) | PPARAPPARGFFAR1LMNAL3MBTL1 | |
| SCHEMBL4453569 | 0.77 | PPARG (0.72) | PPARAPPARGPPARDEPHX2 | |
| SCHEMBL12191490 | 0.77 | PPARG (0.72) | PPARAPPARGPPARDEPHX2 | |
| SCHEMBL6817238 | 0.77 | ACE (0.54) | PPARG | |
| SCHEMBL6817237 | 0.77 | ACE (0.54) | PPARG | |
| SCHEMBL6378617 | 0.75 | LDHA (0.76) | PPARAPPARGPPARDFFAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237857-A1 | NEW PHENALKYLOXY-PHENYL DERIVATIVES | AstraZeneca AB (SE) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001040170-A1 | NEW PHENALKYLOXY-PHENYL DERIVATIVES | ASTRAZENECA AB (SE) | 2001-06-07 | — | — | WO | disclosed |