Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.34 |
| ▸ | SELE | P16581 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 5/20 | 0.33 |
| ▸ | HTR3A | P46098 | 5/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL576144 | 0.82 | SLC6A4 (0.47) | SLC6A4SLC6A3SLC6A2HPGDHTR1A | |
| SCHEMBL13433038 | 0.77 | CHRNA7 (0.41) | SLC6A4SLC6A3SLC6A2HPGDSMN1; SMN2 | |
| SCHEMBL575848 | 0.74 | NPC1 (0.44) | SLC6A4SLC6A3SLC6A2HPGDSMN1; SMN2 | |
| SCHEMBL18508629 | 0.72 | MAPT (0.39) | SLC6A4SLC6A3SLC6A2HPGDPKM | |
| SCHEMBL21205123 | 0.71 | MAPT (0.36) | SLC6A4SLC6A3SLC6A2HPGDSMN1; SMN2 | |
| SCHEMBL7643228 | 0.70 | ICAM1 (0.42) | HPGDSMN1; SMN2ICAM1SELEVCAM1 | |
| SCHEMBL12819994 | 0.68 | CYP2A6 (0.47) | MAPTMEN1ALOX15KMT2AHSD17B10 | |
| SCHEMBL11578003 | 0.67 | MAPT (0.50) | SLC6A4SLC6A3SLC6A2HPGDPKM | |
| SCHEMBL11576431 | 0.67 | HPGD (0.46) | SLC6A4SLC6A3SLC6A2HPGDPKM | |
| SCHEMBL18795381 | 0.67 | SLC6A4 (0.47) | SLC6A4SLC6A3SLC6A2HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181296-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000075145-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-12-14 | — | — | WO | disclosed |