Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9616978 | 0.81 | CYP3A4 (0.57) | CYP3A4CYP2D6ADAM17MTNR1BTRPV1 | |
| SCHEMBL7626318 | 0.78 | CYP3A4 (0.53) | CYP3A4CYP2D6ADAM17MTNR1BTRPV1 | |
| SCHEMBL7627140 | 0.76 | CYP3A4 (0.51) | CYP3A4CYP2D6ADAM17MTNR1BTRPV1 | |
| SCHEMBL7625282 | 0.75 | CYP3A4 (0.49) | CYP3A4CYP2D6ADAM17MTNR1BTRPV1 | |
| SCHEMBL7626298 | 0.74 | CYP3A4 (0.56) | CYP3A4CYP2D6ADAM17TRPV1NPC1 | |
| Trepipam SCHEMBL11704977 | 0.74 | CYP2D6 (1.00) | CYP3A4CYP2D6KDM4ETSHRHSD17B10 | |
| Trepipam SCHEMBL29374758 | 0.74 | CYP2D6 (1.00) | CYP3A4CYP2D6KDM4ETSHRHSD17B10 | |
| SCHEMBL7620240 | 0.74 | CYP3A4 (0.48) | CYP3A4CYP2D6ADAM17MTNR1BTRPV1 | |
| Trepipam SCHEMBL29401068 | 0.74 | CYP2D6 (0.82) | CYP3A4CYP2D6TRPV1KDM4ETSHR | |
| SCHEMBL10746034 | 0.73 | CYP3A4 (0.56) | CYP3A4CYP2D6ADAM17MTNR1BTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020019389-A1 | Urea derivative useful as an anti-cancer agent and process for preparing same | CHACONNE NSI CO., LTD. (KR) | 2002-02-14 | — | — | US | claimed |
| US-20020019389-A1 | Urea derivative useful as an anti-cancer agent and process for preparing same | CHACONNE NSI CO., LTD. (KR) | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019389-A1 | Urea derivative useful as an anti-cancer agent and process for preparing same | UTS2R, SLC14A1, URB2 | CYP3A4 1639/4885CYP2D6 1945/4885ADAM17 4595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.