SCHEMBL76211

SCHEMBL76211

OC(c1ccc(Cl)cc1)C(Cl)(Cl)Cl

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.58
MAPK1 P28482 3/20 0.58
HIF1A Q16665 3/20 0.58
TDP1 Q9NUW8 2/20 0.58
LMNA P02545 2/20 0.58
TP53 P04637 1/20 0.58
HPGD P15428 1/20 0.58
ALDH1A1 P00352 1/20 0.44
ADRB2 P07550 1/20 0.41
CYP2A6 P11509 1/20 0.40
AOC3 Q16853 1/20 0.39
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
BRD4 O60885 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC5 Q9UQL6 1/20 0.39
IDO1 P14902 1/20 0.38
TDO2 P48775 1/20 0.38
CYP19A1 P11511 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7120983 0.80 ESR1 (0.62) TSHRHIF1ATDP1LMNAHPGD
SCHEMBL1508521 0.78 TSHR (0.44) TSHRMAPK1HIF1ATDP1LMNA
SCHEMBL21626316 0.78 TSHR (0.44) TSHRMAPK1HIF1ATDP1LMNA
SCHEMBL1154594 0.78 AOC3 (0.47) TSHRMAPK1HIF1ATDP1LMNA
SCHEMBL23149894 0.78 AOC3 (0.38) TSHRMAPK1HIF1ATDP1LMNA
SCHEMBL23149895 0.78 AOC3 (0.38) TSHRMAPK1HIF1ATDP1LMNA
SCHEMBL12791298 0.78 AOC3 (0.47) TSHRMAPK1HIF1ATDP1LMNA
SCHEMBL23149874 0.78 AOC3 (0.38) TSHRMAPK1HIF1ATDP1LMNA
SCHEMBL21508213 0.78 TSHR (0.44) TSHRMAPK1HIF1ATDP1LMNA
SCHEMBL11302427 0.78 HPGD (0.44) TSHRMAPK1HIF1ATDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107924124-B Negative photoresist composition for I-line with excellent etching resistance 荣昌化学制品株式会社 2020-12-15 CN claimed
CN-104557449-A Synthetic method of stable isotope deuterium-labeled DDT SHANGHAI RES INST CHEMICAL IND 2015-04-29 CN claimed
CN-1029120-C Process for preparing 1, 1-di (chlorophenyl) -2, 2, 2-trichloroethanol ATOCHEM (FR) 1995-06-28 CN claimed
EP-0248954-B1 PROCESS FOR REDUCING THE AMOUNT OF DDT-RELATED IMPURITIES IN 1,1-BIS(CHLOROPHENYL)-2,2,2-TRICHLORO-ETHANOL ROHM AND HAAS COMPANY (US) 1992-04-01 EP claimed
US-5081319-A Isolation and purification SOCIEDAD ESPANOLA DE DESARROLLOS QUIMICOS S.A. (ES) 1992-01-14 US claimed
CN-1057450-A 1, the method for making of 1-two (chloro-phenyl-)-trichloro-ethyl alcohol ATOCHEM (FR) 1992-01-01 CN claimed
EP-0460977-A1 Process for reducing the amount of DDT-related impurities in 1,1-bis (chlorophenyl)-2,2,2-trichloroethanol ROHM AND HAAS COMPANY (US) 1991-12-11 EP claimed
CN-1050014-A Process for preparing 1, 1-bis (4-chlorophenyl) -2, 2, 2-trichloroethanol ATOCHEM (FR) 1991-03-20 CN claimed
EP-0248954-A1 Process for reducing the amount of DDT-related impurities in 1,1-bis(chlorophenyl)-2,2,2-trichloro-ethanol ROHM AND HAAS COMPANY (US) 1987-12-16 EP claimed
CN-114624214-A Paper-based fluorescence method for detecting trichlorfon 中国科学院大连化学物理研究所 2022-06-14 CN disclosed
CN-113637642-A Hybridoma cell strain capable of secreting monoclonal antibody of dicofol and application of hybridoma cell strain 江南大学 2021-11-12 CN disclosed
CN-108291055-B Sulfur-containing compounds as solvents 诺华丝国际股份有限公司 2021-07-06 CN disclosed
CN-112707851-A Sulfur-containing compounds as solvents 诺华丝国际股份有限公司 2021-04-27 CN disclosed
CN-112368336-A Resin composition and cured film thereof 东丽株式会社 2021-02-12 CN disclosed
CN-87100180-A Micro plastic structure and manufacturing method thereof 1987-08-19 CN disclosed
EP-0011279-B1 PROCESS FOR THE PREPARATION OF AROMATICALLY SUBSTITUTED ACETIC ACIDS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1982-05-05 EP disclosed
US-4268442-A REACTING AN AROMATIC ALKEHYDE WITH A TRIHALOMETHANE AND AN ALKANETHIOL IN THE PRESENCE OF A BASE AND AN APROTIC SOLVENT SAGAMI CHEMICAL RESEARCH CENTER (JP) 1981-05-19 US disclosed
US-4210668-A Insecticidal carbamates E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-07-01 US disclosed
EP-0011279-A1 Process for the preparation of aromatically substituted acetic acids SAGAMI CHEMICAL RESEARCH CENTER (JP) 1980-05-28 EP disclosed
US-3966824-A BIODEGRADABLE INSECTICIDES UNIVERSITY OF ILLINOIS FOUNDATION (US) 1976-06-29 US disclosed