Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.62 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | THPO | P40225 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL76211 | 0.80 | TSHR (0.58) | ESR1ESR2HIF1ATSHRALOX15 | |
| SCHEMBL23149894 | 0.78 | AOC3 (0.38) | ESR1ESR2HIF1ATSHRKDM4E | |
| SCHEMBL23149874 | 0.78 | AOC3 (0.38) | ESR1ESR2HIF1ATSHRKDM4E | |
| SCHEMBL23149895 | 0.78 | AOC3 (0.38) | ESR1ESR2HIF1ATSHRKDM4E | |
| SCHEMBL11302427 | 0.78 | HPGD (0.44) | ESR1ESR2HIF1ATSHRTDP1 | |
| SCHEMBL23172374 | 0.77 | AOC3 (0.47) | NFKB1TSHRALOX15KDM4ECYP3A4 | |
| SCHEMBL7434679 | 0.77 | AOC3 (0.47) | NFKB1TSHRALOX15KDM4ECYP3A4 | |
| SCHEMBL4372186 | 0.77 | AOC3 (0.47) | NFKB1TSHRALOX15KDM4ECYP3A4 | |
| SCHEMBL8580685 | 0.77 | ESR1 (0.65) | ESR1ESR2PDCD1CD274TAAR1 | |
| SCHEMBL44658 | 0.77 | ESR1 (1.00) | ESR1ESR2PDCD1CD274TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030144541-A1 | Process for preparing alpha-halogenated retones | RHODIA CHIMIE (FR) | 2003-07-31 | — | — | US | claimed |
| EP-1250303-A1 | METHOD FOR PREPARING ALPHA-HALOGENATED KETONES | RHODIA CHIMIE (FR) | 2002-10-23 | — | — | EP | claimed |
| WO-2001055067-A1 | METHOD FOR PREPARING ALPHA-HALOGENATED KETONES | RHODIA CHIMIE (FR) | 2001-08-02 | — | — | WO | claimed |
| US-4249015-A | Preparation of organic acids and/or esters | SHELL OIL COMPANY (US) | 1981-02-03 | — | — | US | claimed |
| JP-58052236-A | — | — | None | — | — | JP | disclosed |
| JP-56016464-A | — | — | None | — | — | JP | disclosed |
| US-20030144541-A1 | Process for preparing alpha-halogenated retones | RHODIA CHIMIE (FR) | 2003-07-31 | — | — | US | disclosed |
| EP-1250303-A1 | METHOD FOR PREPARING ALPHA-HALOGENATED KETONES | RHODIA CHIMIE (FR) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001055067-A1 | METHOD FOR PREPARING ALPHA-HALOGENATED KETONES | RHODIA CHIMIE (FR) | 2001-08-02 | — | — | WO | disclosed |
| US-4544766-A | HYDROLYSIS OF DICHLOROETHENYL COMPOUND | OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) | 1985-10-01 | — | — | US | disclosed |
| US-4504678-A | Pure crystalline racemic sodium parahydroxymandelate, process for its preparation and uses thereof | SOCIETE FRANCAISE HOECHST (FR) | 1985-03-12 | — | — | US | disclosed |
| US-4408070-A | SODIUM P-FORMYLPHENOLATE | SOCOETE FRANCAISE HOECHST (FR) | 1983-10-04 | — | — | US | disclosed |
| JP-S5852236-A | DICHLOROSTYRENE DERIVATIVE AND ITS PREPARATION | SHIYOUNO TAMIE | 1983-03-28 | — | — | JP | disclosed |
| JP-S5616464-A | PRODUCTION OF ALPHA-METHYLTHIO-4-HYDROXYPHENYLACETIC ACID | NIPPON SODA CO LTD | 1981-02-17 | — | — | JP | disclosed |
| US-4249015-A | Preparation of organic acids and/or esters | SHELL OIL COMPANY (US) | 1981-02-03 | — | — | US | disclosed |
| US-4105857-A | CONDENSING PHENOL AND CHLORAL IN A SULFURIC ACID- METHYLENE CHLORIDE SOLVENT SYSTEM | GENERAL ELECTRIC COMPANY (US) | 1978-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144541-A1 | Process for preparing alpha-halogenated retones | ADH1A, ADH1C, RER1 | ESR1 1300/4885ESR2 765/4885PDCD1 3152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.