Sugi Predict

Sugi Predict / Compounds / SCHEMBL7621153

SCHEMBL7621153

SCHEMBL7621153

CC(C)(C)c1ccc(OP(Oc2ccc(C(C)(C)C)cc2C(C)(C)C)c2ccc(-c3ccc(P(Oc4ccc(C(C)(C)C)cc4C(C)(C)C)c4ccc(-c5ccc(P(Oc6ccc(C(C)(C)C)cc6C(C)(C)C)Oc6ccc(C(C)(C)C)cc6C(C)(C)C)cc5)cc4)cc3)cc2)c(C(C)(C)C)c1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 1/20 0.33
▸ CA2 P00918 1/20 0.33
▸ CA9 Q16790 1/20 0.33
▸ APEX1 P27695 1/20 0.32
▸ KIF11 P52732 2/20 0.32
▸ KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29355846 0.95 CA1 (0.35) CA1CA2CA9APEX1KIF11
SCHEMBL205802 0.95 CA1 (0.35) CA1CA2CA9APEX1KIF11
SCHEMBL7615609 0.95 APEX1 (0.34) CA1CA2CA9APEX1KIF11
SCHEMBL29939280 0.91 CA1 (0.38) CA1CA2CA9APEX1KDM4E
SCHEMBL9298561 0.91 CA1 (0.38) CA1CA2CA9APEX1KDM4E
SCHEMBL13259674 0.90 CA1 (0.35) CA1CA2CA9APEX1KIF11
SCHEMBL1132092 0.90 APEX1 (0.36) CA1CA2CA9APEX1KIF11
SCHEMBL13574881 0.89 CA1 (0.37) CA1CA2CA9APEX1KDM4E
SCHEMBL14454211 0.89 RARA (0.33) CA1CA2CA9APEX1KIF11
SCHEMBL12861914 0.89 NR1I2 (0.34) CA1CA2CA9APEX1KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6465548-B1 6-HYDROXYCHROMAN DERIVATIVE WITH PHOSPHORUS AND PHENOLIC ANTIOXIDANTS; HEAT, LIGHT AND OXIDATION STABILITY DURING MOLDING YOSHITOMI FINE CHEMICALS, LTD. (JP) 2002-10-15 — — US claimed
US-6465548-B1 6-HYDROXYCHROMAN DERIVATIVE WITH PHOSPHORUS AND PHENOLIC ANTIOXIDANTS; HEAT, LIGHT AND OXIDATION STABILITY DURING MOLDING YOSHITOMI FINE CHEMICALS, LTD. (JP) 2002-10-15 — — US disclosed
US-6437164-B1 REACTING BIPHENYL AND PHOSPHORUS TRICHLORIDE IN PRESENCE OF ALUMINUM CHLORIDE, ADDING PYRIDINE, RESULTING DICHLOROPHOSPHINE IS REACTED WITH A PHENOL, REMOVING FORMED PYRIDINE-ALUMINUM CHLORIDE COMPLEX YOSHITOMI FINE CHEMICALS, LTD. (JP) 2002-08-20 — — US disclosed
EP-1142898-A1 PROCESS FOR THE PREPARATION OF PHOSPHONITE COMPOUNDS Yoshitomi Fine Chemicals, Ltd. (JP) 2001-10-10 — — EP disclosed
EP-0719781-B1 Phosphonous, phosphinous or phosphonic acid derivatives as stabilizers for organic materials YOSHITOMI PHARMACEUTICAL (JP) 1999-03-17 — — EP disclosed
EP-0719781-A1 Phosphonous, phosphinous or phosphonic acid derivatives as stabilizers for organic materials YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1996-07-03 — — EP disclosed