Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL762484 | 0.94 | TLR7 (0.44) | TLR7KDM4EHPGDMEN1KMT2A | |
| SCHEMBL822576 | 0.85 | HPGD (0.55) | TLR7KDM4EHPGDMEN1KMT2A | |
| SCHEMBL10084264 | 0.80 | PDE4B (0.47) | TLR7KDM4EHPGDMAPTALDH1A1 | |
| SCHEMBL762155 | 0.77 | KDM4E (0.41) | TLR7KDM4EHPGDMEN1KMT2A | |
| SCHEMBL762055 | 0.77 | KMT2A (0.50) | TLR7KDM4EHPGDMEN1KMT2A | |
| SCHEMBL13625405 | 0.76 | KDM4E (0.52) | TLR7KDM4EHPGDMEN1KMT2A | |
| SCHEMBL762336 | 0.75 | KDM4E (0.52) | TLR7KDM4EHPGDMEN1KMT2A | |
| SCHEMBL762492 | 0.75 | HPGD (0.43) | TLR7KDM4EHPGDMEN1KMT2A | |
| SCHEMBL764064 | 0.74 | PDE4B (0.47) | TLR7KDM4EHPGDMAPTALDH1A1 | |
| SCHEMBL16692180 | 0.74 | KDM4E (0.48) | TLR7KDM4EHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138303-B2 | Polymers | BASF SE (DE) | 2012-03-20 | — | — | US | disclosed |
| US-20100249349-A1 | Novel Polymers | UDC IRELAND LIMITED (IE) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249349-A1 | Novel Polymers | OCIAD2, OCIAD1, SLCO4C1 | TLR7 610/4885KDM4E 3738/4885HPGD 1199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.