SCHEMBL7621639

SCHEMBL7621639

Nc1c(-c2ccccc2)n[nH]c(=O)c1Cl

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.61
ATM Q13315 1/20 0.61
KDM4E B2RXH2 6/20 0.56
ALDH1A1 P00352 5/20 0.56
HPGD P15428 4/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
GAA P10253 3/20 0.56
HSD17B10 Q99714 2/20 0.56
NPC1 O15118 2/20 0.56
RAB9A P51151 2/20 0.56
CDK8 P49336 1/20 0.54
CDK5 Q00535 1/20 0.54
CLK4 Q9HAZ1 1/20 0.54
XDH P47989 4/20 0.53
LMNA P02545 2/20 0.47
GLA P06280 1/20 0.47
POLB P06746 1/20 0.46
MAPT P10636 1/20 0.46
ALOX15 P16050 1/20 0.46
MEN1 O00255 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7617054 0.86 CDK8 (0.57) NPSR1ATMKDM4EALDH1A1HPGD
SCHEMBL3988734 0.84 NPSR1 (0.61) NPSR1ATMKDM4EALDH1A1HPGD
Hydrochloric Acid SCHEMBL2650936 0.82 NPSR1 (0.65) NPSR1ATMKDM4EALDH1A1HPGD
SCHEMBL11444451 0.79 NPSR1 (0.61) NPSR1ATMKDM4EALDH1A1HPGD
SCHEMBL10818030 0.79 NPSR1 (0.56) NPSR1ATMKDM4EALDH1A1HPGD
SCHEMBL2650149 0.76 CLK4 (0.57) NPSR1ATMKDM4EALDH1A1HPGD
SCHEMBL581143 0.76 NPSR1 (1.00) NPSR1ATMKDM4EALDH1A1HPGD
SCHEMBL29870198 0.76 NPSR1 (1.00) NPSR1ATMKDM4EALDH1A1HPGD
SCHEMBL10784410 0.76 NPSR1 (0.51) NPSR1ATMKDM4EALDH1A1HPGD
SCHEMBL4059335 0.75 CDK8 (0.60) NPSR1ATMKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1165520-A1 METHOD FOR PRODUCING 4-AMINO-5-CHLORO-1-PHENYL PYRIDAZINONE-(6) BASF AKTIENGESELLSCHAFT (DE) 2002-01-02 EP disclosed
WO-2000059891-A1 METHOD FOR PRODUCING 4-AMINO-5-CHLORO-1-PHENYL PYRIDAZINONE-(6) BASF AKTIENGESELLSCHAFT (DE) 2000-10-12 WO disclosed
EP-0026847-A1 Process for preparing 4-amino-5-chloro-1-phenylpyridazone-(6) BASF Aktiengesellschaft (DE) 1981-04-15 EP disclosed
EP-0017001-A1 Herbicides in the form of an aqueous suspension containing a pyridazone and a thiolcarbamate, a chloroacetanilide or a dinitroaniline, and a method for their preparation and its use in combating undesired plant growth BASF Aktiengesellschaft (DE) 1980-10-15 EP disclosed