SCHEMBL7621650

SCHEMBL7621650

N[C@H](C(=O)O)C(C(=O)O)C1CCCCC1

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.45
SLC1A3 P43003 6/20 0.44
SLC1A2 P43004 6/20 0.44
SLC1A1 P43005 6/20 0.44
DPP4 P27487 9/20 0.43
ALDH1A1 P00352 1/20 0.41
GRM2 Q14416 1/20 0.38
DPP7 Q9UHL4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7621655 1.00 EPHX1 (0.45) EPHX1SLC1A3SLC1A2SLC1A1DPP4
SCHEMBL3450600 0.89 SLC7A5 (0.40) SLC1A3SLC1A2SLC1A1GRM2
SCHEMBL7120046 0.84 EPHX1 (0.48) EPHX1DPP4ALDH1A1
SCHEMBL15668891 0.84 EPHX1 (0.48) EPHX1DPP4ALDH1A1
SCHEMBL30093936 0.81 EPHX1 (0.44) EPHX1DPP4ALDH1A1
SCHEMBL6843635 0.81 EPHX1 (0.43) EPHX1SLC1A3SLC1A2SLC1A1DPP4
SCHEMBL24520309 0.80 SLC1A3 (0.50) EPHX1SLC1A3SLC1A2SLC1A1DPP4
SCHEMBL2679604 0.80 SLC1A3 (0.50) EPHX1SLC1A3SLC1A2SLC1A1DPP4
SCHEMBL6978063 0.80 SLC1A3 (0.50) EPHX1SLC1A3SLC1A2SLC1A1DPP4
SCHEMBL2679602 0.80 SLC1A3 (0.50) EPHX1SLC1A3SLC1A2SLC1A1DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111372942-A β -catenin function modulating agents and methods thereof 弗格制药有限公司 2020-07-03 CN claimed
CN-111372942-A β -catenin function modulating agents and methods thereof 弗格制药有限公司 2020-07-03 CN disclosed
EP-0497368-B1 CNP analog peptides and their use SUNTORY LTD (JP) 2002-06-12 EP disclosed
US-5434133-A C-type naturiuretic peptide, suppress vascular smooth muscle cell growth SUNTORY LIMITED (JP) 1995-07-18 US disclosed
EP-0556405-A1 PSEUDOPENTAPEPTIDES WITH IMMUNOMODULATING ACTIVITY Japan Tobacco Inc. (JP) 1993-08-25 EP disclosed
WO-1993004080-A1 PSEUDOPENTAPEPTIDES WITH IMMUNOMODULATING ACTIVITY JAPAN TOBACCO INC. (JP) 1993-03-04 WO disclosed
EP-0497368-A1 CNP analog peptides and their use SUNTORY LIMITED (JP) 1992-08-05 EP disclosed