Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 6/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 6/20 | 0.44 |
| ▸ | DPP4 | P27487 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7621650 | 1.00 | EPHX1 (0.45) | EPHX1SLC1A3SLC1A2SLC1A1DPP4 | |
| SCHEMBL3450600 | 0.89 | SLC7A5 (0.40) | SLC1A3SLC1A2SLC1A1GRM2 | |
| SCHEMBL7120046 | 0.84 | EPHX1 (0.48) | EPHX1DPP4ALDH1A1 | |
| SCHEMBL15668891 | 0.84 | EPHX1 (0.48) | EPHX1DPP4ALDH1A1 | |
| SCHEMBL30093936 | 0.81 | EPHX1 (0.44) | EPHX1DPP4ALDH1A1 | |
| SCHEMBL6843635 | 0.81 | EPHX1 (0.43) | EPHX1SLC1A3SLC1A2SLC1A1DPP4 | |
| SCHEMBL24520309 | 0.80 | SLC1A3 (0.50) | EPHX1SLC1A3SLC1A2SLC1A1DPP4 | |
| SCHEMBL2679604 | 0.80 | SLC1A3 (0.50) | EPHX1SLC1A3SLC1A2SLC1A1DPP4 | |
| SCHEMBL6978063 | 0.80 | SLC1A3 (0.50) | EPHX1SLC1A3SLC1A2SLC1A1DPP4 | |
| SCHEMBL2679602 | 0.80 | SLC1A3 (0.50) | EPHX1SLC1A3SLC1A2SLC1A1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497368-B1 | CNP analog peptides and their use | SUNTORY LTD (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-5434133-A | C-type naturiuretic peptide, suppress vascular smooth muscle cell growth | SUNTORY LIMITED (JP) | 1995-07-18 | — | — | US | disclosed |
| EP-0497368-A1 | CNP analog peptides and their use | SUNTORY LIMITED (JP) | 1992-08-05 | — | — | EP | disclosed |