Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7621660 | 1.00 | OPRM1 (0.51) | OPRM1OPRK1OPRD1 | |
| SCHEMBL6653618 | 0.92 | OPRM1 (0.48) | OPRM1OPRK1OPRD1 | |
| SCHEMBL6653615 | 0.92 | OPRM1 (0.48) | OPRM1OPRK1OPRD1 | |
| SCHEMBL7619540 | 0.91 | OPRM1 (0.47) | OPRM1OPRK1OPRD1 | |
| SCHEMBL7619546 | 0.91 | OPRM1 (0.47) | OPRM1OPRK1OPRD1 | |
| SCHEMBL7619453 | 0.90 | OPRM1 (0.52) | OPRM1OPRD1 | |
| SCHEMBL7619449 | 0.90 | OPRM1 (0.52) | OPRM1OPRD1 | |
| SCHEMBL7623433 | 0.86 | OPRM1 (0.44) | OPRM1OPRK1OPRD1 | |
| SCHEMBL7623428 | 0.86 | OPRM1 (0.44) | OPRM1OPRK1OPRD1 | |
| SCHEMBL6532475 | 0.86 | OPRM1 (0.69) | OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441000-B1 | DISEASES MEDIATED BY OPIATE RECEPTORS | PFIZER INC | 2002-08-27 | — | — | US | disclosed |
| EP-1055668-A1 | New 4-arylpiperidine derivatives for the treatment of pruritus | PFIZER INC. (US) | 2000-11-29 | — | — | EP | disclosed |