Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.40 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL7594601 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TSHRMEN1KMT2ATHRB | |
| SCHEMBL1401440 | 0.94 | TSHR (0.65) | ALDH1A1TSHRMEN1KMT2ATHRB | |
| SCHEMBL7777622 | 0.94 | TSHR (0.65) | ALDH1A1TSHRMEN1KMT2ATHRB | |
| Di(Hydroxyethyl)Ether SCHEMBL13516981 | 0.94 | TSHR (0.65) | ALDH1A1TSHRMEN1KMT2ATHRB | |
| Methyl Alcohol SCHEMBL16095002 | 0.94 | ALDH1A1 (0.63) | ALDH1A1TSHRMEN1KMT2ATHRB | |
| SCHEMBL273114 | 0.94 | TSHR (0.65) | ALDH1A1TSHRMEN1KMT2ATHRB | |
| SCHEMBL15136261 | 0.94 | TSHR (0.65) | ALDH1A1TSHRMEN1KMT2ATHRB | |
| SCHEMBL5498331 | 0.94 | ALDH1A1 (0.68) | ALDH1A1TSHRMEN1KMT2ATHRB | |
| SCHEMBL570790 | 0.94 | ALDH1A1 (0.68) | ALDH1A1TSHRMEN1KMT2ATHRB | |
| Alcohol SCHEMBL28157424 | 0.94 | ALDH1A1 (0.68) | ALDH1A1TSHRMEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6454817-B1 | IMMERSING ROLLED ALUMINUM ELECTROLYTIC CAPACITOR IN CONDUCTIVE POLYANILINE EMERALDINE BASE POWDER SOLUTION, DRYING TO FULLY REMOVE THE SOLVENT, SEALING ALUMINUM CAN WITH EPOXY RESIN | SAMWHA ELECTRIC CO., LTD. (KR) | 2002-09-24 | — | — | US | disclosed |