Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 8/20 | 0.46 |
| ▸ | THRB | P10828 | 8/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.44 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7622400 | 1.00 | THRA (0.46) | THRATHRBHSD17B3HAO1S1PR2 | |
| SCHEMBL7623199 | 1.00 | THRA (0.46) | THRATHRBHSD17B3HAO1S1PR2 | |
| SCHEMBL7615734 | 0.94 | THRA (0.49) | THRATHRBHSD17B3HAO1 | |
| SCHEMBL7620050 | 0.94 | THRA (0.49) | THRATHRBHSD17B3HAO1 | |
| SCHEMBL7619952 | 0.93 | THRA (0.47) | THRATHRBHSD17B3HAO1 | |
| SCHEMBL7707971 | 0.90 | THRA (0.45) | THRATHRBHSD17B3HAO1S1PR2 | |
| SCHEMBL7616848 | 0.89 | S1PR1 (0.47) | THRATHRBS1PR2S1PR1S1PR3 | |
| SCHEMBL7623202 | 0.89 | S1PR1 (0.47) | THRATHRBS1PR2S1PR1S1PR3 | |
| SCHEMBL7620688 | 0.89 | S1PR1 (0.47) | THRATHRBS1PR2S1PR1S1PR3 | |
| SCHEMBL15894876 | 0.88 | THRA (0.46) | THRATHRBHSD17B3HAO1S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372800-B1 | IMMUNOSUPPRESSIVE EFFECT AND IS USEFUL AS AN INHIBITOR FOR THE REJECTION REACTION OCCURRING IN ORGAN OR BONE MARROW TRANSPLANTATION, AND AS A PREVENTIVE OR REMEDY FOR ARTICULAR RHEUMATISM, ATOPIC ECZEMA (DERMATITIS), BEHCET'S DISEASE, | MITSUBISHI PHARMA CORPORATION (JP) | 2002-04-16 | — | — | US | disclosed |
| EP-0778263-B1 | BENZENE COMPOUND AND MEDICINAL USE THEREOF | WELFIDE CORP (JP) | 2002-01-09 | — | — | EP | disclosed |
| US-6187821-B1 | SUCH AS 2-AMINO-2-(3-(4-HEPTYLPHENYL)PROPYL)BUTANE-1,4-DIOL; IMMUNOSUPPRESSANT; ADMINISTERING TO TREAT OR PREVENT AUTOIMMUNE DISEASES AND ALLERGIES | WELFIDE CORPORATION (JP) | 2001-02-13 | — | — | US | disclosed |
| US-5948820-A | IMMUNOSUPPRESSANT; PREVENT REJECTION OF ORGAN TRANSPLANT;AUTOIMMUNE DISEASES; MULTIPLE SCLEROSIS; LUPUS; ANTIALLERGENS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-07 | — | — | US | disclosed |
| EP-0778263-A1 | BENZENE COMPOUND AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-11 | — | — | EP | disclosed |