Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 known ✓ | P03956 | 2/20 | 0.32 |
| ▸ | MMP8 known ✓ | P22894 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | LAP3 | P28838 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL26929100 | 0.97 | PPARD (0.37) | PPARDTSHRALDH1A1CA2PLA2G2A | |
| Alcohol SCHEMBL26929079 | 0.97 | PPARD (0.37) | PPARDTSHRALDH1A1CA2PLA2G2A | |
| Alcohol SCHEMBL26929125 | 0.97 | PPARD (0.37) | PPARDTSHRALDH1A1CA2PLA2G2A | |
| Propane SCHEMBL4629637 | 0.90 | CA2 (0.35) | PPARDTSHRCA2PLA2G2AMAPT | |
| SCHEMBL28223995 | 0.87 | CA2 (0.43) | TSHRALDH1A1CA2MMP1MMP2 | |
| SCHEMBL47754 | 0.87 | — | — | |
| Phosphoric Acid Monomethyl Ester SCHEMBL31621719 | 0.84 | — | — | |
| SCHEMBL11677707 | 0.83 | — | — | |
| Phosphoric Acid SCHEMBL2899922 | 0.83 | CA2 (0.40) | TSHRALDH1A1CA2FDPS | |
| SCHEMBL9583822 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577562-B1 | Biodegradable plastic materials, method of producing them, and their use | MAZZUCCHELLI 1849 SPA (IT) | 2002-10-16 | — | — | EP | claimed |
| US-5376708-A | Biodegradable plastic materials, method of producing them, and their use | BATTELLE INSTITUTE E.V. (DE) | 1994-12-27 | — | — | US | claimed |
| EP-0577562-A1 | Biodegradable plastic materials, method of producing them, and their use | BATTELLE MEMORIAL INSTITUTE (CH) | 1994-01-05 | — | — | EP | claimed |
| EP-0577562-B1 | Biodegradable plastic materials, method of producing them, and their use | MAZZUCCHELLI 1849 SPA (IT) | 2002-10-16 | — | — | EP | disclosed |
| EP-0577562-A1 | Biodegradable plastic materials, method of producing them, and their use | BATTELLE MEMORIAL INSTITUTE (CH) | 1994-01-05 | — | — | EP | disclosed |