Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 7/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.40 |
| ▸ | SELP | P16109 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7628994 | 1.00 | HMGCR (0.44) | HMGCRPTPN7SELPMEN1FAAH | |
| SCHEMBL7620562 | 0.93 | HMGCR (0.41) | HMGCRPTPN7SELPMEN1FAAH | |
| SCHEMBL7625844 | 0.93 | HMGCR (0.41) | HMGCRPTPN7SELPMEN1FAAH | |
| SCHEMBL7626022 | 0.86 | TSHR (0.41) | MEN1FAAHTP53CYP1A2CYP3A4 | |
| SCHEMBL7622725 | 0.86 | TSHR (0.41) | MEN1FAAHTP53CYP1A2CYP3A4 | |
| SCHEMBL7628957 | 0.86 | TSHR (0.41) | MEN1FAAHTP53CYP1A2CYP3A4 | |
| SCHEMBL7625993 | 0.86 | TSHR (0.41) | MEN1FAAHTP53CYP1A2CYP3A4 | |
| SCHEMBL7624132 | 0.86 | TSHR (0.41) | MEN1FAAHTP53CYP1A2CYP3A4 | |
| SCHEMBL7620509 | 0.86 | TSHR (0.41) | MEN1FAAHTP53CYP1A2CYP3A4 | |
| SCHEMBL7619796 | 0.86 | TSHR (0.41) | MEN1FAAHTP53CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444832-B1 | OSTEOPOROSIS | ESSWEIN ANGELIKA (DE) | 2002-09-03 | — | — | US | disclosed |