Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7625993 | 1.00 | TSHR (0.41) | TSHRKMT2ASOAT1MEN1FAAH | |
| SCHEMBL7620509 | 1.00 | TSHR (0.41) | TSHRKMT2ASOAT1MEN1FAAH | |
| SCHEMBL7622725 | 1.00 | TSHR (0.41) | TSHRKMT2ASOAT1MEN1FAAH | |
| SCHEMBL7628957 | 1.00 | TSHR (0.41) | TSHRKMT2ASOAT1MEN1FAAH | |
| SCHEMBL7619796 | 1.00 | TSHR (0.41) | TSHRKMT2ASOAT1MEN1FAAH | |
| SCHEMBL7624132 | 1.00 | TSHR (0.41) | TSHRKMT2ASOAT1MEN1FAAH | |
| SCHEMBL7621552 | 1.00 | TSHR (0.41) | TSHRKMT2ASOAT1MEN1FAAH | |
| SCHEMBL27510155 | 0.90 | KMT2A (0.36) | TSHRKMT2ASOAT1MEN1FAAH | |
| SCHEMBL7620580 | 0.89 | FAAH (0.58) | KMT2ASOAT1MEN1FAAHTP53 | |
| SCHEMBL7771202 | 0.89 | FAAH (0.58) | KMT2ASOAT1MEN1FAAHTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444832-B1 | OSTEOPOROSIS | ESSWEIN ANGELIKA (DE) | 2002-09-03 | — | — | US | disclosed |
| EP-0865422-B1 | USE OF AMINOALCOHOLDERIVATIVES AS DRUGS, DERIVATIVES AND PROCESS FOR THEIR PREPARATION | ROCHE DIAGNOSTICS GMBH (DE) | 2001-07-11 | — | — | EP | disclosed |
| EP-0865422-A1 | AMINO ALCOHOL DERIVATIVES, METHODS OF PRODUCING SAID DERIVATIVES AND MEDICAMENTS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997019909-A1 | AMINO ALCOHOL DERIVATIVES, METHODS OF PRODUCING SAID DERIVATIVES AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |