Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 15/20 | 0.40 |
| ▸ | FNTA | P49354 | 2/20 | 0.40 |
| ▸ | FNTB | P49356 | 2/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7632603 | 0.86 | MEN1 (0.43) | RETFNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL7628308 | 0.86 | FNTA (0.41) | RETFNTAFNTBPGGT1B | |
| SCHEMBL7622910 | 0.86 | FNTA (0.38) | RETFNTAFNTBPGGT1B | |
| SCHEMBL7626194 | 0.86 | CBX7 (0.39) | RETFNTAFNTBPGGT1B | |
| SCHEMBL7622760 | 0.86 | MEN1 (0.40) | RETFNTAFNTBPGGT1B | |
| SCHEMBL7683560 | 0.85 | FFAR4 (0.38) | RETNSD2GPR119 | |
| SCHEMBL7622639 | 0.85 | MEN1 (0.41) | RETFNTAFNTBPGGT1B | |
| SCHEMBL7688046 | 0.85 | GCK (0.42) | RETNSD2GPR119 | |
| SCHEMBL7624855 | 0.84 | FNTA (0.38) | RETFNTAFNTBPGGT1B | |
| SCHEMBL7621679 | 0.84 | FNTA (0.37) | RETFNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020193283-A1 | Inhibitors of prenyl-protein transferase | DINSMORE CHRISTOPHER J (US) | 2002-12-19 | — | — | US | claimed |
| WO-2001060458-A2 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-08-23 | — | — | WO | claimed |
| US-20020193283-A1 | Inhibitors of prenyl-protein transferase | DINSMORE CHRISTOPHER J (US) | 2002-12-19 | — | — | US | disclosed |
| WO-2001060458-A2 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193283-A1 | Inhibitors of prenyl-protein transferase | FNTA, FNTB, PTAR1 | RET 3570/4885FNTA 1/4885FNTB 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.