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Sugi Predict / Targets / PTAR1

PTAR1

Protein prenyltransferase alpha subunit repeat-containing protein 1 · Q7Z6K3 · PTAR1 on Sugi Atlas →

0 patent compounds predicted against PTAR1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to PTAR1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effects of Statin and Ezetimibe Association on Kinetics of Artificial Chilomicrons PHASE4COMPLETED
Efficacy of Lapaquistat Acetate and Atorvastatin on Blood Cholesterol Levels in Subjects With Primary Hypercholesterolemia PHASE3COMPLETED
Safety and Efficacy of Lapaquistat Acetate Taken Alone and With Atorvastatin in Subjects With Primary Dyslipidemia PHASE3COMPLETED
NEO100 and High-Grade Meningioma PHASE2RECRUITING
Safety and Efficacy Study in Recurrent or Progressive Grade III or IV IDH1 Mutated Glioma PHASE1/PHASE2RECRUITING
Phase II Study of Simvastatin Plus Irinotecan, Fluorouracil, and Leucovorin(FOLFIRI) for Metastatic CRC PHASE2COMPLETED
Simvastatin + Cetuximab/Irinotecan in K-ras Mutant Colorectal Cancer (CRC) PHASE2COMPLETED
Neoadjuvant Zoledronate and Atorvastatin in Triple Negative Breast Cancer PHASE2COMPLETED
Efavirenz for Patients With Alzheimer's Disease PHASE1COMPLETED
Epidemiology of Atherosclerosis nanCOMPLETED
Exome Sequencing in Autistic Spectrum Disorder nanCOMPLETED
Genetic Analyses of Nonsyndromic and Syndromic Deafness in Pakistan nanENROLLING_BY_INVITATION
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders nanCOMPLETED
Gene Expression in Obesity and Insulin Resistance nanCOMPLETED
Investigation of Copy Number Variations and Genetic Variants in POI nanRECRUITING
Genetic Study of Sitosterolemia nanCOMPLETED
Study of Mycobacterial Infections nanRECRUITING
Identification of Genes and Pathogenesis Involved in Familial Thoracic Aortic Aneurysm nanCOMPLETED
Genetic Analysis of Hereditary Disorders of Hearing and Balance nanCOMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Genetic Mechanisms of Chronic Obstructive Pulmonary Disease (COPD) nanCOMPLETED
Familial Partial Lipodystrophy Study nanCOMPLETED
Gene Polymorphisms Influencing Steroid Synthesis and Action nanWITHDRAWN
Use of Blood Biomarkers for the Early Diagnosis of Hepatocellular Carcinoma (HCC) nanUNKNOWN
Chronic Obstructive Pulmonary Disease Gene Localization nanCOMPLETED
Vitreous Proteomics of Patients Suffering From Pseudoexfoliation Syndrome nanACTIVE_NOT_RECRUITING
Genetic Diagnosis in Congenital Cataracts nanCOMPLETED
Study of a Candidate Gene Involved in Goldenhar Syndrome. nanCOMPLETED
Mechanisms of Inherited Retinal Dystrophies Using Whole Genome Sequencing and in Vitro and in Vivo Models nanCOMPLETED
Gut Microbiome in Patients With Polycystic Ovary Syndrome nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a PTAR1 binder may also engage these)

ProteinNameSimilarity
METTL16 RNA N(6)-adenosine-methyltransferase METTL16 0.959 landscape →
Q9CQG2 — 0.956 Q9CQG2 →
Q61239 — 0.954 Q61239 →
Q5ZIA0 — 0.951 Q5ZIA0 →
Q04631 — 0.951 Q04631 →
P29702 — 0.950 P29702 →
Q0IHB3 — 0.949 Q0IHB3 →
FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 0.948 landscape →
Q9UPR3 — 0.948 Q9UPR3 →
Q8BKT7 — 0.947 Q8BKT7 →
A3KPW7 — 0.947 A3KPW7 →
Q6ZPY2 — 0.946 Q6ZPY2 →
Q4R8W3 — 0.946 Q4R8W3 →
P21580 — 0.945 P21580 →
Q2KHT6 — 0.944 Q2KHT6 →
Q1A730 — 0.943 Q1A730 →
Q8R092 — 0.942 Q8R092 →
O94888 — 0.942 O94888 →
Q6DC64 — 0.942 Q6DC64 →
A1L3L1 — 0.942 A1L3L1 →
Q5REY7 — 0.942 Q5REY7 →
Q148V7 — 0.942 Q148V7 →
Q9P260 — 0.941 Q9P260 →
Q68FX7 — 0.941 Q68FX7 →
Q1RMS8 — 0.941 Q1RMS8 →
Q8VE33 — 0.941 Q8VE33 →
Q8NFG4 — 0.940 Q8NFG4 →
Q13769 — 0.940 Q13769 →
Q7Z624 — 0.939 Q7Z624 →
Q1RMZ1 — 0.939 Q1RMZ1 →