Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7622680 | 1.00 | CA1 (0.58) | CA1CA2BCHEACHEPTGS2 | |
| SCHEMBL13957543 | 0.82 | PTGS2 (0.60) | PTGS2KDM4EALDH1A1APPMAOB | |
| SCHEMBL1876079 | 0.80 | NR1I2 (0.49) | ACHETSHR | |
| SCHEMBL1876077 | 0.80 | NR1I2 (0.49) | ACHETSHR | |
| SCHEMBL4998682 | 0.79 | PTGS2 (0.57) | CA1CA2BCHEACHEPTGS2 | |
| SCHEMBL4998683 | 0.79 | PTGS2 (0.57) | CA1CA2BCHEACHEPTGS2 | |
| SCHEMBL23699095 | 0.79 | PTGS2 (0.55) | PTGS2APPMAOBFBP1PTGS1 | |
| SCHEMBL23699094 | 0.79 | PTGS2 (0.55) | PTGS2APPMAOBFBP1PTGS1 | |
| SCHEMBL8408256 | 0.78 | APP (0.58) | BCHEPTGS2APPMAOBFBP1 | |
| SCHEMBL6791134 | 0.76 | PTGS2 (0.60) | PTGS2ALDH1A1APPMAOBFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020127487-A1 | Bisazo compound and electrophotographic photoconductor using the same | RICOH COMPANY, LTD. (JP) | 2002-09-12 | — | — | US | disclosed |
| US-6448384-B1 | ELECTROSTATIC PROPERTIES, WITH RESPECT TO THE PHOTOSENSITIVITY, ACCEPTANCE POTENTIAL, RETENTIVITY OF CHARGE, POTENTIAL STABILITY, RESIDUAL POTENTIAL, AND SPECTRAL SENSITIVITY | RICOH COMPANY, LTD. (JP) | 2002-09-10 | — | — | US | disclosed |
| US-6333439-B1 | 1,4-BIS(4-(4-NITROPHENYL)-1,3-BUTADIENYL)BENZENE INTERMEDIATE | RICOH COMPANY, LTD. (JP) | 2001-12-25 | — | — | US | disclosed |
| US-6132914-A | Bisazo compound and electrophotographic photoconductor using the same | RICOH COMPANY, LTD. (JP) | 2000-10-17 | — | — | US | disclosed |