SCHEMBL7622686

SCHEMBL7622686

CCN(CC)CC(=O)CC(N)=O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.35
MAPT P10636 4/20 0.35
LMNA P02545 3/20 0.35
MAPK1 P28482 2/20 0.35
CYP3A4 P08684 1/20 0.35
MC4R P32245 1/20 0.35
SCN4A P35499 1/20 0.35
MC3R P41968 1/20 0.35
HTR3A P46098 1/20 0.35
SCN5A Q14524 1/20 0.35
SCN9A Q15858 1/20 0.35
SCN3A Q9NY46 1/20 0.35
HPGD P15428 4/20 0.34
GAA P10253 2/20 0.34
BLM P54132 1/20 0.34
NPSR1 Q6W5P4 1/20 0.33
KDM4E B2RXH2 2/20 0.32
AGTR1 P30556 1/20 0.32
TSHR P16473 2/20 0.32
OPRK1 P41145 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL177796 0.79
SCHEMBL31602039 0.79 TDP1 (0.39) ALDH1A1MAPTLMNAMAPK1CYP3A4
SCHEMBL14331808 0.78 LDHA (0.38) ALDH1A1MAPTLMNAMAPK1CYP3A4
Hydrochloric Acid SCHEMBL3453649 0.77 CHRM2 (0.38) ALDH1A1MAPTLMNAMAPK1CYP3A4
SCHEMBL4449358 0.75 MAPT (0.32) ALDH1A1MAPTLMNACYP3A4HPGD
SCHEMBL1427782 0.75 GABRR1 (0.35) ALDH1A1MAPTLMNAMAPK1CYP3A4
SCHEMBL13685451 0.74 TDP1 (0.33) LMNABLMKDM4ETSHRCHRM2
SCHEMBL18902827 0.74 CHRM2 (0.39) ALDH1A1MAPTLMNAMAPK1CYP3A4
SCHEMBL6656901 0.74 TDP1 (0.50) ALDH1A1MAPTLMNAMAPK1CYP3A4
SCHEMBL5664190 0.73 PAOX (0.37) ALDH1A1LMNAMAPK1HPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0996606-B1 CATALYSED FLUORINATION OF CARBONYL COMPOUNDS F2 CHEMICALS LTD (GB) 2002-01-16 EP disclosed
US-6300511-B1 FLUORINATING CARBONYL COMPOUND BY REPLACEMENT OF ALPHA-HYDROGEN ATOM WITH FLUORINE COMPRISING REACTING COMPOUND WITH FLUORINATING AGENT IN PRESENCE OF CATALYTICALLY EFFECTIVE AMOUNT OF TRANSITION METAL-CONTAINING CATALYST F2 CHEMICALS LIMITED (GB) 2001-10-09 US disclosed
EP-0996606-A1 CATALYSED FLUORINATION OF CARBONYL COMPOUNDS F2 Chemicals Ltd. (GB) 2000-05-03 EP disclosed
WO-1999003802-A1 CATALYSED FLUORINATION OF CARBONYL COMPOUNDS F2 CHEMICALS LIMITED (GB) 1999-01-28 WO disclosed