Kaempferol

Kaempferol

SCHEMBL7622850

[2H]Oc1c(-c2ccc(O)cc2)oc2cc(O)cc(O)c2c1=O

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 9/20 0.84
▸ KMT2A Q03164 9/20 0.84
▸ CYP1A2 P05177 8/20 0.84
▸ ABCB1 P08183 7/20 0.84
▸ CYP3A4 P08684 7/20 0.84
▸ CYP1A1 P04798 7/20 0.84
▸ CYP1B1 Q16678 7/20 0.84
▸ CYP2C9 P11712 6/20 0.84
▸ FTO Q9C0B1 6/20 0.84
▸ KDM4E B2RXH2 6/20 0.84
▸ XDH P47989 6/20 0.84
▸ MAPT P10636 5/20 0.84
▸ CYP2D6 P10635 5/20 0.84
▸ ALOX15 P16050 5/20 0.84
▸ HSD17B10 Q99714 5/20 0.84
▸ APP P05067 5/20 0.84
▸ BCHE P06276 4/20 0.84
▸ ACHE P22303 4/20 0.84
▸ CYP2C19 P33261 4/20 0.84
▸ TP53 P04637 4/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Kaempferol SCHEMBL30864674 1.00 MEN1 (0.84) MEN1KMT2ACYP1A2ABCB1CYP3A4
Kaempferol SCHEMBL30655455 0.91 MEN1 (1.00) MEN1KMT2ACYP1A2ABCB1CYP3A4
Kaempferol SCHEMBL1259228 0.91 MEN1 (1.00) MEN1KMT2ACYP1A2ABCB1CYP3A4
Kaempferol SCHEMBL18817 0.91 MEN1 (1.00) MEN1KMT2ACYP1A2ABCB1CYP3A4
Kaempferol SCHEMBL29378805 0.91 MEN1 (1.00) MEN1KMT2ACYP1A2ABCB1CYP3A4
Kaempferol SCHEMBL31749037 0.90 MEN1 (0.97) MEN1KMT2ACYP1A2ABCB1CYP3A4
Kaempferol SCHEMBL34461912 0.90 MEN1 (0.97) MEN1KMT2ACYP1A2ABCB1CYP3A4
Kaempferol SCHEMBL31256029 0.90 MEN1 (0.97) MEN1KMT2ACYP1A2ABCB1CYP3A4
Kaempferol SCHEMBL17237761 0.90 MEN1 (0.97) MEN1KMT2ACYP1A2ABCB1CYP3A4
Kaempferol SCHEMBL38651062 0.90 MEN1 (0.97) MEN1KMT2ACYP1A2ABCB1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1245230-A2 Amentoflavone as an antiviral agent Advanced Life Sciences Inc. (US) 2002-10-02 — — EP disclosed
US-20020068757-A1 Biflavanoids and derivatives thereof as antiviral agents ADVANCED LIFE SCIENCES, INC. 2002-06-06 — — US disclosed
US-6399654-B1 ADMINISTERING MIXTURE OF VIRICIDE AND BIOFLAVANOID ADVANCED LIFE SCIENCES, INC. 2002-06-04 — — US disclosed
US-5948918-A PLANT EXTRACTS MEDICHEM RESEARCH, INC. (US) 1999-09-07 — — US disclosed
US-5773462-A INFLUENZA THERAPY MEDICHEM RESEARCH, INC. (US) 1998-06-30 — — US disclosed
WO-1997000679-A1 BIFLAVANOIDS AND DERIVATIVES THEREOF AS ANTIVIRAL AGENTS MEDICHEM RESEARCH, INC. (US) 1997-01-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020068757-A1 Biflavanoids and derivatives thereof as antiviral agents HK2, GYS2, HK1 MEN1 836/4885KMT2A 463/4885CYP1A2 199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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